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The Administrative Core will be responsible for overseeing the daily functions of the Center programs in fulfilling the goal of the Center. The Core will provide administrative support, including support for grants and financial management; scheduling of meetings and seminars; coordination of activities between the Center and UCLA academic and administrative bodies and other participating institutions (LA BioMed Research Institute at Harbor-UCLA Medical Center, and the VA Greater Los Angeles Healthcare System-West Los Angeles). The Core will also provide biostatistical support for all research projects and cores, and the management of research data and shared data function of the Center. It will have the ultimate responsibility of managing details of the budget, appropriately filing budgetary information, and will file progress reports and communicate with NCCAM. The scheduling, dissemination of information, and organization of the Center Symposium, including the participation of the External Advisory Board, will also be the responsibilities of the Administrative Core. Oversight all of the established policies for recruitment of women and minorities, and interaction with other NCCAM Centers for Excellence will also be the responsibilities of the Administrative Core. The Administrative Core, under the direction of Dr. Vay Liang W. Go, will provide support as well as oversight of the research projects and cores, and Dr. Gang Li will provide biostatistical support: The research projects are: Project 1 on the effects of phytonutrients and metabolism on pancreatic cancer, Project 2 on how polyphenols regulate lipid inflammatory process in pancreatic cancer, and Project 3 on flavonoids in pancreatic carcinogenesis and angiogenesis. The projects will utilize our shared core resources including the Animal Model Core, Phytonutrient Core, and Metabolomics Core. The Administrative Core will also interact and collaborate with key investigators and have access to their available shared resources at UCLA and participating institutions to fulfill the Center's goal to study phytonutrient mechanisms of action in inflammatory and proliferative diseases of the pancreas. It is our goal to have the results of this investigation characterize the metabolic phenotypes in response to specific phytonutrients and so that it can form the rationale for biologically-based practices in the prevention and treatment of pancreatic diseases.
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