Administrative Core/Go, Vay Liang

行政核心/Go，Vay Liang

• 批准号: 7394049
• 负责人: Vay Liang W Go
• 金额: $ 11.86万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-12-01 至 2012-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7394049
• 关键词: Animal Model; Budgets; Data; Disease; Flavonoids; Goals; Grant; Healthcare Systems; Inflammatory; Institution; Investigation; Lipids; Los Angeles; Malignant neoplasm of pancreas; Medical center; Metabolic; Metabolism; Minority; National Center for Complementary and Alternative Medicine; Occupational activity of managing finances; Pancreas; Pancreatic Diseases; Phenotype; Policies; Prevention; Process; Progress Reports; Research; Research Institute; Research Personnel; Research Project Grants; Resource Sharing; Resources; Schedule; Support of Research; Woman; angiogenesis; base; carcinogenesis; daily functioning; gang; information organization; metabolomics; polyphenol; programs; response; symposium

The Administrative Core will be responsible for overseeing the daily functions of the Center programs in fulfilling the goal of the Center. The Core will provide administrative support, including support for grants and financial management; scheduling of meetings and seminars; coordination of activities between the Center and UCLA academic and administrative bodies and other participating institutions (LA BioMed Research Institute at Harbor-UCLA Medical Center, and the VA Greater Los Angeles Healthcare System-West Los Angeles). The Core will also provide biostatistical support for all research projects and cores, and the management of research data and shared data function of the Center. It will have the ultimate responsibility of managing details of the budget, appropriately filing budgetary information, and will file progress reports and communicate with NCCAM. The scheduling, dissemination of information, and organization of the Center Symposium, including the participation of the External Advisory Board, will also be the responsibilities of the Administrative Core. Oversight all of the established policies for recruitment of women and minorities, and interaction with other NCCAM Centers for Excellence will also be the responsibilities of the Administrative Core. The Administrative Core, under the direction of Dr. Vay Liang W. Go, will provide support as well as oversight of the research projects and cores, and Dr. Gang Li will provide biostatistical support: The research projects are: Project 1 on the effects of phytonutrients and metabolism on pancreatic cancer, Project 2 on how polyphenols regulate lipid inflammatory process in pancreatic cancer, and Project 3 on flavonoids in pancreatic carcinogenesis and angiogenesis. The projects will utilize our shared core resources including the Animal Model Core, Phytonutrient Core, and Metabolomics Core. The Administrative Core will also interact and collaborate with key investigators and have access to their available shared resources at UCLA and participating institutions to fulfill the Center's goal to study phytonutrient mechanisms of action in inflammatory and proliferative diseases of the pancreas. It is our goal to have the results of this investigation characterize the metabolic phenotypes in response to specific phytonutrients and so that it can form the rationale for biologically-based practices in the prevention and treatment of pancreatic diseases.

行政核心将负责监督中心项目的日常职能 实现中心的目标。核心将提供行政支助，包括支助赠款和 财务管理；安排会议和研讨会；协调中心之间的活动 和加州大学洛杉矶分校的学术和行政机构以及其他参与机构(洛杉矶生物医学研究 港湾-加州大学洛杉矶分校医疗中心研究所和退伍军人管理局大洛杉矶医疗系统-西洛杉矶 洛杉矶)。核心还将为所有研究项目和核心提供生物统计支持， 研究数据的管理和中心的数据共享功能。它将承担最终的责任 管理预算细节，适当提交预算信息，并将提交进度报告 并与NCCAM进行通信。信息的安排、传播和组织 中心专题讨论会，包括外部咨询委员会的参与，也将是责任 管理核心。监督招募妇女和少数群体的所有既定政策， 与其他NCCAM卓越中心的互动也将是 管理核心。行政核心，在魏良伟博士的指导下，将提供 支持和监督研究项目和核心，李刚博士将提供生物统计学 支持：研究项目1：植物营养素和代谢对胰腺的影响 癌症，多酚如何调节胰腺癌脂质炎症过程的项目2，以及项目3 黄酮类化合物在胰腺癌发生和血管生成中的作用。这些项目将利用我们的共享核心 资源包括动物模型核心、植物营养核心和代谢组学核心。这个 管理核心还将与主要调查人员互动和协作，并可以访问他们的 加州大学洛杉矶分校和参与机构的可用共享资源，以实现中心的研究目标 植物营养素在胰腺炎症和增殖性疾病中的作用机制。这是我们的目标 为了让这项研究的结果表征特定反应的代谢表型 植物营养素，因此它可以形成以生物为基础的实践的基础，在预防和 胰腺疾病的治疗。