A Multilevel HIV-Prevention Strategy for High-Risk Youth

针对高危青少年的多层次艾滋病毒预防策略

• 批准号: 7274748
• 负责人: DANIEL ROMER
• 金额: $ 62.46万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-28 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7274748
• 关键词: AIDS prevention; Abstinence; Adolescent; Adoption; Affect; African American; Age; Attitude; Behavior; Belief; Chlamydia; Cities; Communities; Condition; Cross-Sectional Studies; Detection; Digit structure; Effectiveness of Interventions; Epidemic; Exhibits; Expectancy; Geographic Locations; Gonorrhea; HIV; Health Promotion; Incidence; Intervention; Joints; Low income; Maca; Mass Media; Media Campaign; Media Intervention; Mediating; Methodology; Modeling; Outcome; Patient Self-Report; Prevention intervention; Prevention strategy; Preventive; Randomized; Randomized Controlled Clinical Trials; Rate; Recruitment Activity; Research; Research Personnel; Risk; Risk Reduction; Role; Self Efficacy; Sex Behavior; Sexually Transmitted Diseases; Specimen; Surveys; Telephone Interviews; Testing; Time; Training; Trichomonas; Urine; Youth; base; community organizations; design; disorder prevention; follow-up; peer; programs; protective behavior; safer sex; skills; skills training; social; therapy design; transmission process

DESCRIPTION (provided by applicant): This multisite project provides a unique test of a multilevel HIV/STD prevention strategy for high-risk youth. A total of 1600 African American adolescents, ages 12-16, will be recruited through CBOs in 4 cities, two in the Northeast (Providence and Syracuse) and two in the Southeast (Columbia and Macon), to participate in this HIV/STD prevention trial. Adolescents will complete a baseline ACASI administered survey to assess their attitudes, beliefs and sexual behaviors, and provide a urine specimen for detection of three prevalent STDs. Following baseline assessment, all adolescents will be randomly assigned to receive either the Focus on Kids HIV-prevention intervention or a General Health Promotion control. Subsequently, adolescents will be followed longitudinally and complete similar assessments at 6-, 12- and 18-months follow-up. The second level of intervention involves tailored HIV/STD prevention messages through local mass media. One city in each regional city-pair will be randomly assigned to receive the HIV prevention media campaign while the other city will serve as a control city (no media campaign). Thus, the media messages will be directed to African American youth in only one of the two cities in each geographic region. The media program will deliver HIV-prevention messages that are culturally sensitive and age appropriate; these programs will promote both abstinence and risk reduction practices. Cross-sectional surveys of 1200 African American youth using random-digit-dialing telephone interviews in the two cities that receive the media campaign and the two media control cities will be conducted over a 30-month period to determine the community-wide effects of the HIV media campaign. This design will enable a test of the joint and separate effects of the two interventions over an 18-month follow-up for the youth participating in the small-group interventions. In addition, the media campaign is predicted to independently enhance adolescents' adoption of HIV-preventive attitudes, beliefs and behaviors on a community-wide basis compared to youth in the non-media control cities. Causal modeling methodology will be employed to assess the effects of the two levels of intervention and to identify the role of supportive messages received through the media and from peers that are predicted to maintain safer sexual behavior as adolescents mature.

描述（由申请人提供）：这个多地点项目为高危青少年提供了多层次艾滋病毒/性病预防策略的独特测试。 将通过 4 个城市的社区组织招募总共 1600 名 12 至 16 岁的非裔美国青少年，其中两个在东北部（普罗维登斯和锡拉丘兹），两个在东南部（哥伦比亚和梅肯），参加这项艾滋病毒/性病预防试验。 青少年将完成一项由 ACASI 管理的基线调查，以评估他们的态度、信仰和性行为，并提供尿液样本来检测三种流行的 STD。 基线评估后，所有青少年将被随机分配接受“关注儿童”艾滋病毒预防干预措施或一般健康促进控制措施。随后，将对青少年进行纵向随访，并在 6、12 和 18 个月的随访中完成类似的评估。 第二级干预涉及通过当地大众媒体定制艾滋病毒/性病预防信息。 每个区域城市对中的一个城市将被随机分配接受艾滋病毒预防媒体宣传活动，而另一个城市将作为对照城市（无媒体宣传活动）。 因此，媒体信息将仅针对每个地理区域两个城市之一的非裔美国青年。媒体计划将传递具有文化敏感性且适合年龄的艾滋病毒预防信息；这些方案将促进禁欲和减少风险的做法。 将在 30 个月的时间内对接受媒体宣传活动的两个城市和两个媒体控制城市的 1200 名非裔美国青年进行随机数字拨号电话采访的横断面调查，以确定艾滋病毒媒体宣传活动对社区范围内的影响。 该设计将能够在 18 个月的随访中对参与小组干预的青年进行测试，以测试两种干预措施的联合和单独效果。 此外，与非媒体控制城市的年轻人相比，预计媒体宣传活动将独立提高青少年在社区范围内采取艾滋病毒预防态度、信念和行为的能力。 将采用因果建模方法来评估两个干预水平的效果，并确定通过媒体和同龄人收到的支持信息的作用，这些信息预计将在青少年成熟时保持更安全的性行为。