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BREAST ONCOLOGY PROGRAM

乳腺肿瘤学项目

基本信息

批准号：
7506350
负责人：
JOE W. GRAY
金额：
$ 6.49万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-25 至 2012-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7506350
关键词：
Address Adolescence Age Alternative Splicing Antibodies Area Attention Authorization documentation Award Bacteriophages Basic Cancer Research Basic Science Behavior Benchmarking Benign Biodistribution Bioinformatics Biological Biological Assay Biological Markers Biology Biotechnology Blood Breast Breast Cancer Cell Breast Cancer Early Detection Breast Diseases British Columbia Budgets Cancer Biology Cancer Center Cancer Detection Cancer cell line Caring Cell Line Cells Cellular Assay Cessation of life Characteristics Chemicals Clinic Clinical Clinical Data Clinical Research Clinical Services Clinical Trials Collaborations Collection Communities Community Clinical Oncology Program Comprehensive Cancer Center Computer Simulation Conduct Clinical Trials Consultations Cultured Cells Data Data Set Decision Making Development Diagnostic Disease Disease Attributes Disease Progression Early Detection Research Network Early Diagnosis Environment Epidemiology Epidermal Growth Factor Receptor Foundations Functional disorder Funding Future Gene Expression Genetic Genomics Goals Grant Gray unit of radiation dose Hereditary Malignant Neoplasm High Risk Woman Hospitals Human Image Immunoliposome In Situ In Vitro Individual Information Management Institutes International Intervention Invasive Ions Knowledge Laboratories Ligands Malignant Neoplasms Malignant neoplasm of pancreas Mammary gland Mammography Maps Mass Spectrum Analysis Measurement Medical Methods Modification Molecular Molecular Probes Molecular Profiling Monitor Neoadjuvant Therapy Netherlands Noninfiltrating Intraductal Carcinoma Outcome Palpable Paraffin Pathologist Pathway interactions Patient Preferences Patients Peer Review Performance Pharmaceutical Preparations Phosphorylation Physicians Plasma Population Population Research Prevention Procedures Process Program Research Project Grants Proteomics Publications Quality Control Quality of Care Radiation Rate Registries Reproduction spores Research Research Personnel Resources Risk Risk Assessment Sampling San Francisco Screening for cancer Series Serum Signal Pathway Signal Transduction Signal Transduction Pathway Specimen System Systemic Therapy Systems Biology Technology Technology Assessment Testing Therapeutic Time Tissue Banks Tissues Toxic effect Training Transforming Growth Factor beta Translations Tumor Markers Universities Validation Videotape Woman Work base breast density cancer care cancer cell cancer prevention cancer risk cancer therapy carcinogenesis care delivery design environmental agent epigenomics follow-up glycosylation human tissue improved inhibitor/antagonist malignant breast neoplasm mass spectrometer member mouse model multidisciplinary neoplastic cell novel novel therapeutics outreach parity programs prospective receptor research clinical testing research study response success survivorship therapeutic target therapy development tool tumor tumor progression

项目摘要

The Breast Oncology Program is comprised of 48 Program Members from 18 different UCSF departments. The Program supports and stimulates basic, clinical, and population research in breast cancer and facilitates the translation of these findings into improved cancer management and control. The Program's themes are as follows: (1) epidemiology; (2) carcinogenesis, early detection and cancer prevention; (3) genetics and biology of cancer progression; (4) identification of new therapeutic targets and approaches; and (5) outreach, clinical care delivery and outcomes. Research awards using funds from the SPORE and philanthropic donors that come to the Program from the Cancer Center stimulate research in these theme areas. Research in the Breast Oncology Program is now supported by the Bay Area Breast Cancer SPORE, a DOD Center of Excellence on "A Blueprint For Regional Excellence In Breast Cancer Care," five large multidisciplinary, multi-institutional projects that support work in one or more themes, and by numerous individual investigator-initiated grants. Interactions between Program Members are encouraged in several discussion forums, including a weekly multidisciplinary seminar, an annual retreat, a weekly tumor board, a monthly community forum, and a patient-physician management discussion series. The Program has $11,393,013 Total peer reviewed support for the last budget year. The Program has 18% intra-programmatic and 41% inter-programmatic publications.

乳腺肿瘤学计划由来自18个不同UCSF部门的48名计划成员组成。该计划支持和促进乳腺癌的基础，临床和人口研究，并促进将这些发现转化为改进的癌症管理和控制。该方案的主题是（1）流行病学;（2）致癌、早期发现和癌症预防;（3）遗传学和癌症进展的生物学;（4）新的治疗靶点和方法的鉴定;和（5）外展，临床护理交付和结果。使用SPORE和慈善机构资金的研究奖项来自癌症中心的捐赠者促进了这些主题领域的研究。乳腺肿瘤学项目的研究现在得到了美国国防部下属的海湾地区乳腺癌SPORE的支持卓越中心的“一个蓝图，区域卓越的乳腺癌护理，”五个大型多学科，支持一个或多个主题工作的多机构项目，发起人发起的赠款。在一些讨论中，鼓励计划成员之间的互动论坛，包括每周多学科研讨会，年度务虚会，每周肿瘤委员会，每月社区论坛，和一个病人-医生管理讨论系列。该方案有11，393，013美元上一个预算年度的同行审议支助总额。该方案有18%的方案内和41% 方案间出版物。