INFANT PRIMATE RESEARCH LAB (IPRL)

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。在过去的一年里，多萝西·曼德尔博士成功地实施了一个触摸屏测试系统，以评估90天大的婴儿的认知发展。我们也一直在努力扩展计算机环境中的认知评估系统，以包括对不同水平的执行功能、记忆容量和空间记忆的发展变化敏感的措施。Drs。Burbacher和Grant继续与儿童医院的一组调查人员进行磋商，以开发用于IPRL的新测试程序。吉姆·菲利普斯博士和艾弗里·韦斯博士将提供测试设备和专业知识来研究幼龄灵长类动物动眼肌功能的纵向发展。约翰·凯利博士正在协助设计和实施测试程序，以检查年轻猴子的中央凹发育。我们的数据收集和管理程序也在继续升级。我们已经成功地在实验室中使用了无线技术，现在所有的数据都是通过戴尔笔记本电脑或掌上设备（如Palm Pilots）收集的。2005年，在心理物理学领域的专家Lynne Kiorpes博士和Ron Boothe博士的专业知识下，开发了计算机视觉灵敏度测试设备。实验室人员将继续为附属调查人员提供与生殖生物学计划相关的服务。IPRL的工作人员协助进行月经的日常观察、训练动物抽血、超声波成像和胚胎移植。最后，从2005年5月开始在实验室进行的研究为14名本科生提供了培训机会。该计划在满足大学的主要目标之一方面非常成功，提供高质量的本科研究培训。此外，在进度报告期内，有1名本科荣誉学生和1名研究生从事高级研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. During the past year, Dr. Dorothy Mandell has successfully implemented a touch screen testing system to assess cognitive development with infants as young as 90-days old. We have also been working to expand the cognitive assessment battery in the computer environment to include measures that are sensitive to developmental changes in different levels of executive functioning, memory capacity, and spatial memory. Drs. Burbacher and Grant have continued to consult with a team of investigators from the Children's Hospital to develop new test procedures for use at the IPRL. Dr. Jim Phillips and Dr. Avery Weiss are providing the test equipment and expertise to study the longitudinal development of oculomotor function in infant primates. Dr. John Kelley is assisting with the design and implementation of test procedures to examine foveal development in young monkeys. Upgrades of our data collection and management programs have continued. We have successfully implemented the use of wireless technology in the lab and all data are now collected via DELL laptops or hand-held devices such as Palm Pilots. During 2005, a computerized visual acuity testing apparatus was developed with the expertise of Dr. Lynne Kiorpes and Dr. Ron Boothe, both experts in the field of psychophysics. Laboratory personnel are continuing to offer services to affiliate investigators in conjunction with the Reproductive Biology program. IPRL staff provides assistance with daily observations for menses, training animals for blood draws, ultrasound imaging and embryo transfers. Finally, the studies conducted in the laboratory since May, 2005 provided opportunities for training 14 undergraduate students. This program has been highly successful in meeting one of the major goals of the University, providing quality undergraduate training in research. In addition, one undergraduate honors student and on graduate student engaged in advanced research during the progress report period.