Secondary Prevention of Alcohol Dependence and Depression Among College Students

大学生酒精依赖和抑郁症的二级预防

• 批准号: 7305423
• 负责人: TIBOR P. PALFAI
• 金额: $ 23.36万
• 依托单位: BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7305423
• 关键词: Address; Affective; Alcohol abuse; Alcohol consumption; Alcohol dependence; Alcohols; Characteristics; Classification; Cognition; Cognitive; Condition; Counseling; Development; Disease; Distress; Effectiveness of Interventions; Exhibits; Facility Construction Funding Category; Feedback; Frequencies; Functional disorder; Goals; Health; Heavy Drinking; Intervention; Maintenance; Major Depressive Disorder; Manuals; Measures; Mediator of activation protein; Mental Depression; Mental disorders; Modification; Motivation; National Institute on Alcohol Abuse and Alcoholism; Numbers; Outcome; Participant; Personal Satisfaction; Phase; Pilot Projects; Prevention; Prevention approach; Procedures; Process; Randomized Controlled Trials; Rate; Recurrence; Risk; Role; Secondary Prevention; Source; Staging; Students; Symptoms; System; Testing; Training; Treatment Efficacy; Week; Work; alcohol related problem; base; binge drinking; day; depressive symptoms; disability; disorder risk; drinking; drinking behavior; experience; follow-up; method development; pilot trial; prevent; single episode major depressive disorder; size; subclinical depression; university student

DESCRIPTION (provided by applicant): Project Summary: Alcohol dependence and major depression represent two major sources of distress and disability among college students. Risks for the development of these disorders include hazardous drinking and elevated depressive symptoms respectively, both of which are experienced by a large proportion of college students and place them at risk for a variety of negative academic and interpersonal consequences. Hazardous drinking and elevated depressive symptoms not only increase the risk for the development of alcohol dependence and major depression but also have reciprocal influences on one another in the development, maintenance, and recurrence of these disorders. Finally, hazardous drinking students with elevated subclinical depression symptoms exhibit distinct cognitive motivational characteristics that may influence their ability to change. Given the frequent co-occurrence of elevated depressive symptoms and hazardous drinking, there are a number of advantages to addressing both of the issues in an integrated intervention. The current project seeks to develop a short-term (3-session) intervention to address these objectives. Specifically, this proposal seeks to: (1) develop an integrated short-term secondary prevention approach for alcohol dependence and major depression for college students at risk for these disorders, and (2) conduct a pilot trial to determine effect size estimates of the efficacy of the intervention. During the first phase (Stage 1A) the intervention will be developed and pilot tested with 8 hazardous drinking college students who exhibit mild to moderate depressive symptoms. For the pilot trial (Stage1B), participants will be assigned to either a short-term intervention that is based on systematic motivational counseling (Cox & Klinger, 2004) or an Assessment Only control condition. Alcohol outcomes, depressive symptoms, and hypothesized change processes will be assessed at baseline, 3 and 6 months. Results of this work will provide the basis for a randomized controlled trial to examine the efficacy of this new intervention to prevent the development of alcohol dependence and major depression.

描述（由申请人提供）： 项目概述：酒精依赖和重性抑郁是大学生痛苦和残疾的两个主要来源。这些疾病的发展风险分别包括危险饮酒和抑郁症状升高，这两种情况都是大部分大学生经历的，并使他们面临各种负面学术和人际关系后果的风险。危险饮酒和抑郁症状的升高不仅增加了酒精依赖和重度抑郁症的风险，而且在这些疾病的发展，维持和复发中相互影响。最后，危险饮酒的学生与升高的亚临床抑郁症状表现出明显的认知动机的特点，可能会影响他们的改变能力。鉴于抑郁症状升高和危险饮酒的频繁同时发生，在综合干预中解决这两个问题有许多优点。目前的项目旨在制定一项短期（3次会议）干预措施，以实现这些目标。具体而言，该提案旨在：（1）为有这些疾病风险的大学生制定酒精依赖和重度抑郁症的综合短期二级预防方法，以及（2）进行试点试验，以确定干预效果的效应量估计。在第一阶段（第1A阶段），将制定干预措施，并对8名表现出轻度至中度抑郁症状的危险饮酒大学生进行试点测试。对于先导试验（第1B阶段），参与者将被分配到基于系统动机咨询的短期干预（考克斯和克林格，2004）或仅评估对照条件。将在基线、3个月和6个月时评估酒精结果、抑郁症状和假设的变化过程。这项工作的结果将提供一个随机对照试验的基础，以检查这种新的干预措施，以防止酒精依赖和抑郁症的发展的有效性。