HIGH MAGNETIC FIELD EFFECTS ON RATS

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Dr Smith has been investigating the effects of high magnetic fields on the behavior of conscious rats. Using magnets at the NHMFL, particularly the 600 wide bore, he observes that rats inserted into the magnet will spin in a circle for a couple of minutes when removed, the direction of spinning depending on the magnet polarity. However the orientation and bore size of that magnet limits his studies. Dr Smith has thus begun using the 11.1T/40cm magnet. In his first studies, he repeated his observations of polarity dependant rotation. In a preliminary study, after suspecting dB/dt effects in the ear were causing this behavior, rats were inserted and removed rapidly or slowly from the magnet. The animals inserted slowly slowed a stronger rotation behavior ¿ an unexpected observation. Further studies are being planned.