HIGH MAGNETIC FIELD EFFECTS ON RATS

高磁场对大鼠的影响

• 批准号: 7369586
• 负责人: JAMES SMITH
• 金额: $ 0.58万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7369586
• 关键词: MAGNETIC; FIELD; EFFECTS; RATS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Dr Smith has been investigating the effects of high magnetic fields on the behavior of conscious rats. Using magnets at the NHMFL, particularly the 600 wide bore, he observes that rats inserted into the magnet will spin in a circle for a couple of minutes when removed, the direction of spinning depending on the magnet polarity. However the orientation and bore size of that magnet limits his studies. Dr Smith has thus begun using the 11.1T/40cm magnet. In his first studies, he repeated his observations of polarity dependant rotation. In a preliminary study, after suspecting dB/dt effects in the ear were causing this behavior, rats were inserted and removed rapidly or slowly from the magnet. The animals inserted slowly slowed a stronger rotation behavior ¿ an unexpected observation. Further studies are being planned.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中得到体现。列出的机构是中心的机构，不一定是研究者的机构。史密斯博士一直在研究强磁场对有意识的老鼠行为的影响。他在 NHMFL 使用磁铁，特别是 600 宽孔的磁铁，观察到插入磁铁的老鼠在取出后会绕圈旋转几分钟，旋转的方向取决于磁铁的极性。然而，该磁铁的方向和孔径限制了他的研究。 史密斯博士因此开始使用11.1T/40cm磁铁。在他的第一项研究中，他重复了他对极性相关旋转的观察。在一项初步研究中，在怀疑耳朵中的 dB/dt 效应导致这种行为后，将老鼠插入磁铁并快速或缓慢地从磁铁中取出。插入的动物缓慢地减缓了更强的旋转行为——这是一个意想不到的观察结果。进一步的研究正在计划中。