ACID LOADS IN HIV-INFECTED PATIENTS (PART A) ALSO SEE SPID 0699

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是中心的机构，不一定是研究者的机构。我们将从 HIV 感染者身上采集两份血液样本和两份 24 小时尿液样本，以测试他们的疾病、药物和/或饮食产生的酸负荷是否影响他们的骨代谢。为了避免被误导，我们将同时评估可能影响骨代谢的多个其他因素。这项研究的参与者将被邀请参加一项为期 4 周的单独研究，以观察吞咽抗酸剂是否会改善 HIV 感染者的骨代谢。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We will collect two blood and two 24-hour urine samples from people with HIV infection, to test whether acid loads produced by their illness, medications, and/or diet are affecting their bone metabolism. To avoid being misled, we will simultaneously evaluate multiple other factors that can affect bone metabolism. Participants in this study will be invited to participate in a separate 4-week study to see whether swallowing antacids will improve bone metabolism in HIV-infected patients.