ACID LOADS IN HIV-INFECTED PATIENTS (PART A) ALSO SEE SPID 0699

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。我们将采集HIV感染者的两份血液和两份24小时尿液样本，以测试他们的疾病、药物和/或饮食产生的酸负荷是否影响他们的骨代谢。为了避免被误导，我们将同时评估其他多种可能影响骨代谢的因素。这项研究的参与者将被邀请参加另一项为期4周的研究，看看吞服抗酸剂是否会改善HIV感染患者的骨代谢。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We will collect two blood and two 24-hour urine samples from people with HIV infection, to test whether acid loads produced by their illness, medications, and/or diet are affecting their bone metabolism. To avoid being misled, we will simultaneously evaluate multiple other factors that can affect bone metabolism. Participants in this study will be invited to participate in a separate 4-week study to see whether swallowing antacids will improve bone metabolism in HIV-infected patients.