131I-MIBG WITH INTENSIVE CHEMOTHERAPY AND AUTOLOGOUS STEM CELL RESCUE

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The therapy in this study involves getting a new drug that is radioactive. The radioactive drug (131I-MIBG) is given in hopes that if will cause the cancer cells to die. After this drug is given, the subject will receive three chemotherapy drugs followed by a stem cell transplant with the subject's own cells. This is a Phase II trial looking to see if this treatment gets rid of the cancer cells and what side effects this treatment may cause. We do not know if this therapy will be effective. The total treatment with the radioactive medicine, chemotherapy, stem cell transplant, and recovery time, will take about 6 months.