SLEEP AND MEDICINAL CANNABIS

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。研究药用大麻对患有痛性神经病的HIV阳性患者的客观和主观睡眠质量和数量的间接影响。确定与安慰剂相比，日间药用大麻治疗是否与夜间睡眠效率增加、慢波睡眠增加和快速眼动睡眠百分比减少有关。确定与安慰剂相比，白天服用大麻是否与改善主观夜间睡眠质量有关。具体变化将包括减少睡眠延迟、增加总睡眠时间和提高全球睡眠质量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Examine the indirect effects of medicinal cannabis on objective and subjective sleep quality and quantity in HIV positive patients with painful neuropathy. Determine if daytime medicinal cannabis treatment will be associated with increased nocturnal sleep efficiency, increased slow wave sleep and decreased percentage REM sleep compared to placebo. Determine if daytime cannabis administration will be associated with improved subjective nocturnal sleep quality compared to placebo. Specific changes will include decreased sleep latency, increased total sleep time, and increased global sleep quality.