SHORT TERM EFFECTS OF MEDICINAL CANNABIS ON SPASTICITY IN MULTIPLE SCLEROSIS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。在多发性硬化症痉挛患者中评估17天内吸食药用大麻与安慰剂的安全性和有效性。将强调短期安全性，特别是在神经精神副作用方面。将在安慰剂或活性药物治疗3天前后获得痉挛评级、认知评级和其他总体指标。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Assess the safety and efficacy of smoked medicinal cannabis versus placebo over 17 days in multiple sclerosis patients with spasticity. Short term safety, particularly in terms of neuropsychiatric side effects, will be stressed. Spasticity ratings, cognitive ratings and additional global measures will be obtained before and after treatment with either placebo or active product for 3 days.