CCTG 560A: VIRAL POPULATION KINETICS

CCTG 560A：病毒群体动力学

• 批准号: 7374181
• 负责人: SUSAN E LITTLE
• 金额: $ 3.39万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7374181
• 关键词: RNA; lymph; lymphocyte; plasma; tissues

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Evaluate the rates of HIV production and clearance after initiating or discontinuing antiretroviral treatment. Evaluate the dynamics of different virus populations (according to resistance pattern or host cell) after initiating or discontinuing antiretroviral treatment. Evaluate viral populations in lymph tissue in subjects with and without detectable HIV RNA in the plasma, and evaluate viral populations in lymphocytes when HIV RNA levels are undetectable in the plasma.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。评估在开始或停止抗逆转录病毒治疗后艾滋病毒的产生和清除率。评价开始或停止抗逆转录病毒治疗后不同病毒种群的动态（根据耐药模式或宿主细胞）。评价血浆中有和无可检出HIV RNA的受试者淋巴组织中的病毒种群，并在血浆中HIV RNA水平不可检出时评价淋巴细胞中的病毒种群。