Gratitude in Post MI Patients Effects on Health Related Mood and Clinical Outcome

心肌梗死后患者的感恩对健康相关情绪和临床结果的影响

• 批准号: 8769400
• 负责人: Paul J Mills
• 金额: $ 23.25万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8769400
• 关键词: Adherence; Affect; Aftercare; Alcohol consumption; American; Attitude; Awareness; Behavior; Biological Markers; Blood Pressure; Cardiac; Cardiac rehabilitation; Cardiology; Cardiovascular system; Clinical; Clinical assessments; Confusion; Coupled; Depressed mood; Diet; Environment; Etiology; Event; Exercise; Failure; Fatty acid glycerol esters; Feeling; Fiber; Future; Gifts; Health; Health behavior; Inflammation; Interleukin-6; Intervention; Intervention Studies; Life; Life Style; Link; Measures; Mediating; Mental Health; Methodology; Moods; Myocardial Infarction; Outcome; Patient Self-Report; Patients; Personal Satisfaction; Pharmaceutical Preparations; Physical Function; Population; Psychosocial Assessment and Care; Psychosocial Factor; Recurrence; Reporting; Risk; Severities; Sleep; Smoking; Stress; Testing; Therapeutic Effect; Time; Vision; Walking; anakinra; clinically relevant; coping; emotional distress; experience; fruits and vegetables; gratitude; group intervention; help-seeking behavior; improved; medication compliance; non-compliance; outcome forecast; peace; physical conditioning; post intervention; primary outcome; programs; public health relevance; response; secondary outcome; standard of care; success; trait; willingness

DESCRIPTION (provided by applicant): Every year, nearly 800,000 Americans endure a first myocardial infarction (MI), and over half of those will have a recurrent event. There are numerous factors that influence prognosis following an MI. In addition to physical factors, such as initial MI severity and adherence to medication and cardiac rehabilitation programs, psychosocial factors are highly predictive of future clinical course. Positive affect, finding meaning in the MI event, and in life in general, and managing the consequences and emotional distress of the MI are highly important. Gratitude is typically defined as a feeling or attitude in acknowledgment of a benefit that one has received or will receive, a habitual focusing on and appreciating the positive aspects of life. It is associated with higher levels of subjective well-being, and people who are more grateful experience less stress, are less depressed, have higher levels of control over their environment, have more positive ways of coping with life's difficulties, and have fewer negative coping strategies. Gratitude is correlated with self-reported physical health, and this link is mediated by psychological health, healthy activities, and willingness to seek help for health. Interventions to clinically increase gratitude have shown great promise, demonstrating the ability to increase overall sense of well-being, meaning in life, and potential associations with improved health. In 113 patients within 30 days of a first-time MI, this proposed exploratory intervention study will examine whether an eight-week gratitude journaling intervention coupled with standard of care (SOC), as compared to SOC plus journaling memorable events and SOC alone will increase positive health behaviors, psychological health, and physical functioning. Psychosocial and clinical assessments will be performed over a six-month period, with testing occurring before, immediately after, and four months after treatment. We envision the study's findings will (a) scientifically show evidence of causality in the relationship between gratitude and our clinically relevant endpoints, (b) therapeutically provide a new intervention methodology to harness these benefits in this cardiac population, and (c) show mechanisms that underlie both the natural and therapeutic effects, both to improve scientific understanding and to allow more tailored interventions to be developed at a later date.

描述（由申请人提供）：每年，近80万美国人患有首次心肌梗死（MI），其中一半以上会复发。影响心肌梗死预后的因素有很多。除了生理因素，如初始心肌梗死的严重程度、药物治疗和心脏康复计划的依从性外，心理社会因素对未来的临床病程也有很高的预测作用。积极的影响，在MI事件中找到意义，在一般的生活中，管理MI的后果和情绪困扰是非常重要的。感恩通常被定义为生活中的一种感觉或态度