250 MICROGRAM ACTH STIMULATION TEST IN PREGNANCY

妊娠期 250 微克 ACTH 刺激试验

• 批准号: 7378634
• 负责人: ROY E WEISS
• 金额: $ 1.26万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-18 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7378634
• 关键词: adrenal glands; aldosterone; cortisol; plasma; pregnancy

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. It is hypothesized that pregnant women have significantly elevated total and free cortisol levels and plasma aldosterone concentrations (in comparison to non-pregnant women), and that these levels will increase as pregnancy progresses. It is hypothesized that there will be an increased responsiveness of the adrenal glands to synthetic ACTH in pregnancy, and that particularly free cortisol response to synthetic ACTH will increase as prenancy progresses.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。假设孕妇的总皮质醇水平和血浆醛固酮浓度显着升高（与非孕妇相比），并且随着妊娠的进展，这些水平将增加。假设肾上腺对妊娠合成ACTH的反应能力会增加，并且随着核前前的进展，对合成ACTH的尤其是自由的皮质醇反应将增加。