PACTG 390-COMBINATION ANTIRETROVIRAL REGIMENS (HIV)

PACTG 390-抗逆转录病毒联合治疗方案 (HIV)

• 批准号: 7374950
• 负责人: William Thomas Shearer
• 金额: $ 0.88万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7374950
• 关键词: PACTG; 390; COMBINATION; ANTIRETROVIRAL; REGIMENS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will evaluate two different treatment combinations of anti-HIV drugs, and will use one of two plans for switching from one to the other treatment combinations. One plan will switch treatment combination when the viral load is 1,000 copies of HIV-1 per milliliter of blood in the bloodstream, and the other plan will switch treatment when the viral load is 30,000 copies of HIV-1 per milliliter of blood in the bloodstream. The study will evaluate if there is a difference in benefit for either of the two switching plans in a four-year treatment.

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项研究将评估两种不同的抗艾滋病毒药物治疗组合，并将使用两种计划中的一种来从一种治疗组合切换到另一种治疗组合。一项计划将在病毒载量为每毫升血液中1,000份HIV-1时切换治疗组合，另一项计划将在病毒载量为每毫升血液中30,000份HIV-1时切换治疗方案。这项研究将评估在为期四年的治疗中，这两个转换计划中的任何一个在益处上是否存在差异。