PACTG 390

PACTG 390

• 批准号: 7607605
• 负责人: Juan C Salazar
• 金额: $ 0.51万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607605
• 关键词: Age-Years; Anti-Retroviral Agents; Child; Computer Retrieval of Information on Scientific Projects Database; End Point; Failure; Funding; Grant; HIV; Institution; Nucleosides; Protease Inhibitor; RNA-Directed DNA Polymerase; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Viral Load result; day; non-nucleoside reverse transcriptase inhibitors

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary objectives of this study are: to compare the combination of 2 NRTIs plus a protease inhibitor (PI) versus 2 Nucleoside Reverse Transcriptase (NRTIs) plus a non-nucleoside reverse transcriptase inhibitor (NNRTI) as initial therapy, followed by second-line therapy if failure occurs, in terms of their effects on a long-term virologic endpoint and to compare two different viral load criteria for switching from first-line to second-line therapy in HIV Antiretroviral Naive Children > 30 Days and < 18 years of age.

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