MECHANISMS OF NO-CONTRIBUTION TO REFLEX CUTANEOUS VASODILATION WITH HYPERTENSIO

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究的目的是确定精氨酸酶在健康老年受试者组（65-85岁）与健康年轻受试者组（18-30岁）的反射性皮肤血管舒张中的作用，并研究活性氧在老年受试者组与健康年轻受试者组的反射性皮肤血管舒张中no依赖部分的相对作用。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the study is to determine the role of arginase in reflex cutaneous vasodilation in a healthy aged human subject group (65-85 years old) compared to a healthy young subject group (18-30 years old) and to examine the relative role of reactive oxygen species on the NO-dependent portion of reflex cutaneous vasodilation in an aged humans subject group compared to a healthy young subject group.