MECHANISMS OF THE NO-CONTRIBUTION TO REFLEX CUTANEOUS VASODILATION WITH AGE

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究的目的是确定与健康年轻受试者组（18-30 岁）相比，精氨酸酶在健康老年受试者组（65-85 岁）反射性皮肤血管舒张中的作用，并检查活性氧对老年人受试者组与健康年轻受试者组反射性皮肤血管舒张的 NO 依赖性部分的相对作用。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the study is to determine the role of arginase in reflex cutaneous vasodilation in a healthy aged human subject group (65-85 years old) compared to a healthy young subject group (18-30 years old) and to examine the relative role of reactive oxygen species on the NO-dependent portion of reflex cutaneous vasodilation in an aged humans subject group compared to a healthy young subject group.