RISK AND PREVENTION OF LARGE LOCAL REACTIONS TO INSECT STINGS

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项研究的目的是测试对叮咬有较大局部反应的人是否会在接受蛇毒免疫治疗时产生较小的局部反应。要做到这一点(如果你决定参与)，你可以在接种前在严密的医疗监督下被蜜蜂、黄色夹克、大黄蜂或黄蜂叮咬(根据你之前的反应和昆虫过敏测试结果)，并在接受毒液免疫疗法治疗(或不治疗)一段时间后再次被叮咬。全国大约有200人将参加这项研究，好时医疗中心预计将有大约100人参加。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research is to test whether people who had a large local reaction to a sting will have a smaller local reaction with venom immunotherapy. This is done (if you decide to participate) by having you stung by a honeybee, yellow jacket, hornet, or wasp (based on your previous reaction and your insect allergy test results) under close medical supervision before being immunized and again after a period of treatment (or non-treatment) with venom immunotherapy. Approximately 200 people will take part in this research nationwide and approximately 100 people are expected to take part at the Hershey Medical Center.