RISK AND PREVENTION OF LARGE LOCAL REACTIONS TO INSECT STINGS

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。这项研究的目的是测试对刺痛有较大局部反应的人是否会对毒液免疫疗法产生较小的局部反应。如果你决定参加，在进行免疫接种之前，在密切的医疗监督下，让你被蜜蜂、黄马甲、大黄蜂或黄蜂蜇伤（根据你以前的反应和你的昆虫过敏测试结果），并在一段时间的治疗（或不治疗）后再次进行毒液免疫治疗。全国大约有200人将参加这项研究，预计好时医疗中心将有大约100人参加。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research is to test whether people who had a large local reaction to a sting will have a smaller local reaction with venom immunotherapy. This is done (if you decide to participate) by having you stung by a honeybee, yellow jacket, hornet, or wasp (based on your previous reaction and your insect allergy test results) under close medical supervision before being immunized and again after a period of treatment (or non-treatment) with venom immunotherapy. Approximately 200 people will take part in this research nationwide and approximately 100 people are expected to take part at the Hershey Medical Center.