ROLE OF PSEUDOEPHEDRINE ON PERENNIAL ALLERGIC RHINITIS & ASSOCIATED SLEEP

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 过敏性鼻炎的主要表现之一是充血。 鼻充血易导致睡眠呼吸暂停和微觉醒。 这种睡眠障碍会导致白天嗜睡和疲劳。 使用伪麻黄碱可能有效地减少充血，但客观和主观上，缺乏研究证明减少充血是否会改善睡眠和减少嗜睡。 使用长效减充血剂可能会干扰睡眠。由于长效减充血剂和抗组胺药的大量使用，确定这一点很重要。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. One of the main manifestations of allergic rhinitis is congestion. Nasal congestion can predispose to sleep apnea and microarousals. This sleep disturbance can result in daytime somnolence and fatigue. The use of pseudoephedrine may be effective at reducing congestion, but objectively and subjectively, studies are lacking that demonstrate if the reduction of congestion will result in improved sleep and reduce somnolence. The possibility exists that sleep may be disturbed by use of long acting decongestants. It is important to determine this due to a high use of long acting decongestants and antihistamines.