ACTG A5223: SEX DIFFERENCES IN LOPINAVIR / RITONAVIR PHARMACOKINETICS

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is to evaluate if there are differences in the Lopinavir/Ritonavir blood levels based on the sex of the patient. In addition, this PK study will determine the effect of race, ethnicity, age, weight, body mass index and the use of Tenofovir on the levels of Lopinavir and Ritonavir.