ACTG A5223: SEX DIFFERENCES IN LOPINAVIR / RITONAVIR PHARMACOKINETICS

ACTG A5223：洛匹那韦/利托那韦药代动力学的性别差异

• 批准号: 7608316
• 负责人: PRINCY N KUMAR
• 金额: $ 0.2万
• 依托单位: CHILDREN'S RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7608316
• 关键词: Age; Blood; Body mass index; Computer Retrieval of Information on Scientific Projects Database; Drug Kinetics; Ethnic Origin; Funding; Grant; Institution; Lopinavir/Ritonavir; Patients; Race; Research; Research Personnel; Resources; Sex Characteristics; Source; Tenofovir; United States National Institutes of Health; Weight; base; sex

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is to evaluate if there are differences in the Lopinavir/Ritonavir blood levels based on the sex of the patient. In addition, this PK study will determine the effect of race, ethnicity, age, weight, body mass index and the use of Tenofovir on the levels of Lopinavir and Ritonavir.

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究旨在评价基于患者性别的洛匹那韦/利托那韦血液水平是否存在差异。 此外，这项PK研究将确定人种、种族、年龄、体重、体重指数和使用替诺福韦对洛匹那韦和利托那韦水平的影响。