A5223:SEX DIFFERENCES IN LOPINAVIR/RITONAVIR PHARMACOKINETICS, HIV-1 MEN & WOMEN

A5223：洛匹那韦/利托那韦药代动力学的性别差异，HIV-1 男性

• 批准号: 7608451
• 负责人: PRINCY N KUMAR
• 金额: $ 0.41万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7608451
• 关键词: Age; Blood; Body mass index; Computer Retrieval of Information on Scientific Projects Database; Drug Kinetics; Ethnic Origin; Funding; Grant; HIV-1; Institution; Lopinavir/Ritonavir; Patients; Race; Research; Research Personnel; Resources; Sex Characteristics; Source; Tenofovir; United States National Institutes of Health; Weight; Woman; base; sex

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is to evaluate if there are differences in the Lopinavir/Ritonavir blood levels based on the sex of the patient. In addition, this PK study will determine the effect of race, ethnicity, age, weight, body mass index and the use of Tenofovir on the levels of Lopinavir and Ritonavir.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究是为了评估基于患者的性别的洛匹那韦/利托纳维尔血液水平是否存在差异。 此外，这项PK研究将确定种族，种族，年龄，体重，体重指数的影响以及替诺福韦在洛匹那韦和利托纳维尔水平上的使用。