RECRUITING CORE

招聘核心人员

• 批准号: 7381146
• 负责人: J Donald Capra
• 金额: $ 29.7万
• 依托单位: OKLAHOMA MEDICAL RESEARCH FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381146
• 关键词: RECRUITING; CORE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The selection of the five recruiting packages for this application was an exacting and laborious process. Each of the program heads made a half-day presentation to the steering committee of the present COBRE grant. Drs. Tang, Floyd, Harley, Gorbsky and Kincade argued for a position in their programs. After institutional resources, space and direction was approved, descriptions of the recruits were solicited. We endeavored to recruit scientists jointly whenever possible, as illustrated by the Neuroimmunologist being recruited by the Programs in FRBA/A&I, and the Molecular Biologist being recruited by the Programs in MCDB/I&C (see Recruiting Core, this application). Such joint recruits act to integrate research in individual Programs, serving as conduits between them. Integration of this kind strengthens the researcher by placing him/her in dual research environments, the Programs involved, and the institution as a whole. Importantly, this integration plays a vital role in allowing us to assemble diverse teams of researchers to target complex goals, as illustrated by our emerging Neuroscience Initiative and recent successful U19 award. In each instance, we have provided within the application the justification for the recruit, who will mentor the recruit, and the exact plans for the recruit within our organizational framework. We have also taken heed of the current guidelines that allow at least some allocation of resources to others in an institution not directly connected to the narrow focus of the COBRE program under review. As such, following with our long-range strategic plan to add to our faculty in neuroscience and cell, molecular and developmental biology, we are using four of the recruiting packages to support those efforts. 1) Joint Appointment for a Neuro-immunologist in Free Radical Biology and Aging Program and the Arthritis and Immunology Research Program: OMRF has an outstanding program in Free Radical Biology and Aging. The current six members of the program focus effort on the neuroinflammation that accompanies Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis (ALS). We believe expanding this program by four investigators will bring us to a critical mass in this arena. OMRF also has an outstanding program in Arthritis and Immunology (Drs. James, Harley, Reichlin, Farris, Centola, etc). We have determined that a joint recruit between these two programs would benefit both, and foster communication between two of our highly successful research efforts. The two Programs have determined that such a recruit should be a neuro-immunologist, and it is to support this recruit that we are requesting funds. The full justification for the recruit is found within. Dr. Robert Floyd, head of FRBA, and Dr. Judith James of AI will mentor this recruit. Dr. Kenneth Hensley will serve as junior mentor. Dr. Hensley has been on our faculty for five years, has an R01, and is one of our most cited young investigators. The Steering Committee believes he is ready for this role. We will also enlist the expertise of Dr. Rheal Towner and Dr. Mark Coggeshall (head of the Cell Signaling Core on this application). 2) Addition to the Immunobiology and Cancer Program: Dr. Paul Kincade heads OMRF's Immunobiology and Cancer program. His two recruits over the last seven years, Drs. Mark Coggeshall and Xiao Hong Sun, are among the best additions to our staff in the last decade. Both have successfully transitioned their laboratories to OMRF, both have successfully competed on a national level for funds (six R01s between them), and both have been promoted to full member status. The five-person program (with Drs. Webb and Thompson) deserves an additional colleague. They have outlined in the section on recruiting cores the logic for their choices and the people they will be recruiting. Indeed, this search is well under way. Depending on the recruit, this mentee will be mentored by any member of this distinguished faculty. Likely, Dr. Kincade will take the senior mentorship role and Dr. Sun a junior mentor role. 3) Addition to the Molecular, Cell and Developmental Biology Research Program: A year ago, OMRF recruited Dr. Gary Gorbsky as the new head of MCDB. He is in the process of recruiting new faculty for his program. The major emphasis of the early recruiting will be to add to our strength in developmental biology, especially as we have a world class mouse facility that is functioning well. We have support from the Presbyterian Health Foundation to help recruit individuals with an emphasis in genetics, and seek support from this COBRE to recruit a faculty member with a developmental biology interest, especially one who would collaborate with members of our outstanding Cardiovascular Research Program, Arthritis and Immunology Research Program, or Neuroscience Research Initiative. This recruit falls under the new guidelines for the COBRE that allow recruiting outside the major theme of the COBRE. We will be certain that this recruit is well mentored, and the recruit will have full access to our Core Facilities. This will provide a formal mechanism to include this recruit in the COBRE process. Obviously, the Steering Committee, our External Advisory Committee as well as NCRR will be approached for guidance. 4) Joint appointment to the Immunobiology and Cancer Program and the Molecular Cell and Developmental Biology Research Program: The goal of this recruitment would be to bring someone to our campus who will bridge the research interests of two of our finest programs: IC and MCDB. Here we seek to identify someone who (for example) performs studies employing genetic manipulation of the developing immune system of the mouse, perhaps on the B cell or the T cell side, as we have great depth in B and T cell development, but not at the genetic level. Such a person would fit comfortably in both programs and serve as a conduit for interaction between them. Drs. Kincade and Gorbsky have agreed to undertake this joint recruitment. 5) Addition to the Free Radical Biology and Aging Program: We seek funds to fill a major void at OMRF: a mathematical modeler (with an emphasis in neurobiology). The addition of Dr. Jose Conchello, a mathematician in our imaging group in our Molecular Cell and Developmental Biology Program has impacted our entire Institute, and we seek funds to extend this level of mathematical expertise into neurobiology. The individual who assumes this position will be collaborating with a group of experienced neuroscience researchers already in place at OMRF and OUHSC. We believe this powerful technology needs to be present on our campus and located in the FRBA program. More details are enclosed within. Mentoring someone like this will be complex, as we have no comparable talent at OMRF, however Dr. Thomas Ray, an internationally recognized researcher in the field of computer modeling is located nearby at the University of Oklahoma Norman Campus. Oklahoma. Dr. Conchello as well as Drs. Floyd and Tang should provide the senior level of mentorship we need. If needed we will bring someone here from outside the state on a regular basis to provide mentoring for the recruit.

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。为这一申请选择五个招聘方案是一个严格而费力的过程。每个项目负责人都向COBRE基金的指导委员会做了半天的报告。Drs。唐、弗洛伊德、哈利、戈尔布斯基和金凯德在各自的节目中为自己的立场而争论。在机构资源、空间和方向得到批准后，征集新兵的描述。我们尽可能联合招聘科学家，如FRBA/A&I项目招聘神经免疫学家，MCDB/I&C项目招聘分子生物学家（见招聘核心，本申请）。这种联合招募的行为是将研究整合到各个项目中，作为它们之间的渠道。这种整合通过将他/她置于双重研究环境，所涉及的项目和整个机构中来加强研究人员。重要的是，这种整合在使我们能够聚集不同的研究团队来实现复杂的目标方面发挥着至关重要的作用，正如我们新兴的神经科学计划和最近成功的U19奖所说明的那样。在每个实例中，我们都在应用程序中提供了招聘的理由，谁将指导招聘，以及在我们的组织框架内招聘的确切计划。我们还注意到目前的指导方针，即至少允许将一些资源分配给与正在审查的COBRE项目的狭隘重点没有直接联系的机构中的其他人。因此，按照我们在神经科学、细胞、分子和发育生物学方面增加师资的长期战略计划，我们正在使用四个招聘包来支持这些努力。1)在自由基生物学和衰老项目和关节炎和免疫学研究项目联合任命神经免疫学家：OMRF在自由基生物学和衰老方面有一个突出的项目。目前该项目的六名成员专注于帕金森病、阿尔茨海默病和肌萎缩侧索硬化症（ALS）伴随的神经炎症。我们相信增加四名调查人员会让我们在这个领域达到一个关键的规模。在关节炎和免疫学方面也有出色的项目。James, Harley, Reichlin, Farris， Centola等)。我们已经确定，这两个项目之间的联合招聘将有利于双方，并促进我们两个非常成功的研究成果之间的沟通。这两个项目已经确定这样的新成员应该是神经免疫学家，我们申请资金就是为了支持这个新成员。招聘的充分理由在。FRBA负责人罗伯特·弗洛伊德博士和人工智能的朱迪思·詹姆斯博士将指导这名新兵。肯尼斯·亨斯利博士将担任初级导师。亨斯利博士在我们这里工作了五年，获得了R01，是我们被引用次数最多的年轻研究者之一。指导委员会认为他已经为这一角色做好了准备。我们还将招募Dr. Rheal Towner和Dr. Mark Coggeshall（细胞信号核心的负责人）的专业知识。2)免疫生物学和癌症项目：Paul Kincade博士负责OMRF的免疫生物学和癌症项目。他在过去七年里招募的两名新成员。Mark Coggeshall和Xiao Hong Sun是过去十年来我们最好的员工之一。两者都成功地将其实验室过渡到OMRF，都成功地在国家一级竞争资金（它们之间有6个r01），并且都已晋升为正式成员地位。这个五人项目（博士）。韦伯和汤普森)应该多一个同事。他们在招聘核心部分概述了他们选择的逻辑和他们将招聘的人。事实上，这种搜索正在进行中。根据招聘情况，这些学员将由这所杰出学院的任何成员指导。金凯德博士将担任高级导师，孙博士将担任初级导师。3)除了分子、细胞和发育生物学研究项目：一年前，OMRF聘请加里·戈尔布斯基博士担任MCDB的新负责人。他正在为他的项目招募新的教员。早期招募的主要重点将是增加我们在发育生物学方面的实力，特别是因为我们有一个运行良好的世界级老鼠设施。我们得到了长老会健康基金会的支持，以帮助招募具有遗传学重点的个人，并寻求COBRE的支持，以招募具有发育生物学兴趣的教员，特别是那些将与我们杰出的心血管研究计划，关节炎和免疫学研究计划或神经科学研究计划的成员合作的教员。该招聘符合COBRE的新准则，该准则允许在COBRE的主要主题之外进行招聘。我们会确保这名新员工受到良好的指导，新员工可以完全使用我们的核心设施。这将提供一个正式的机制，将该招聘纳入COBRE流程。显然，指导委员会，我们的外部咨询委员会以及NCRR将寻求指导。4)联合任命免疫生物学和癌症项目以及分子细胞和发育生物学研究项目：此次招聘的目标是将我们两个最好的项目：IC和MCDB的研究兴趣联系起来。在这里，我们试图找到（例如）使用基因操作研究小鼠免疫系统发育的人，可能是在B细胞或T细胞方面，因为我们在B细胞和T细胞发育方面有很大的深度，但不是在遗传水平上。这样的人可以很好地适应这两个项目，并作为他们之间互动的渠道。Drs。金凯德和戈尔布斯基同意联合招募。5)自由基生物学和衰老项目的补充：我们寻求资金来填补OMRF的一个主要空缺：数学建模师（重点是神经生物学）。我们分子细胞和发育生物学项目成像组的数学家Jose Conchello博士的加入对我们整个研究所产生了影响，我们正在寻求资金将这一水平的数学专业知识扩展到神经生物学。担任该职位的个人将与OMRF和OUHSC的一组经验丰富的神经科学研究人员合作。我们认为这项强大的技术需要出现在我们的校园里，并位于FRBA项目中。更多的细节附在里面。指导这样的人将是复杂的，因为我们在OMRF没有类似的人才，然而，国际公认的计算机建模领域的研究人员托马斯·雷博士就在俄克拉何马大学诺曼校区附近。俄克拉何马州。康切洛医生和。弗洛伊德和唐应该提供我们需要的高级指导。如果需要的话，我们会定期从州外派人来为新员工提供指导。