COBRE: MUSC: CORE C: CLINICAL RESOURCES

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。临床资源核心的目标是协调所有Cobre临床活动。临床资源核心中心将提供必要的临床和实验室专业知识，以促进Cobre项目的实施。此外，该中心还将通过南加州大学已有的海岛家庭项目，协调对居住在南卡罗来纳州海岸屏障岛屿(“海岛”)和邻近沿海社区的非裔美国家庭的接触。临床资源核心的具体目标是：-提供门诊牙科临床研究能力以支持所有Cobre项目-按照Cobre临床方案的要求收集人口统计和其他调查数据-为所有Cobre临床调查提供校准的牙科检查员-收集、处理和分发用于实验室分析的生物样本-收集、处理和储存生物样本以供未来研究-按照Cobre临床协议的要求对生物样本进行专门的生物分析，以对南卡罗来纳州海岛上的非裔美国人和讲古拉语的人口进行口腔健康评估，临床资源核心中心的其他具体目标是：-从口腔牙科发现的角度描述这一独特的种族人口的特征-使用龋齿指数(DMFT和DMFT)确定龋齿患病率-确定牙周病的存在-确定软组织病变和癌症的存在-确定这一人群的牙科治疗需求-向受影响的人群提供口腔牙科教育

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of the Clinical Resources Core is to coordinate all COBRE clinical activities. The Clinical Resource Core will provide the necessary clinical and laboratory expertise to facilitate the implementation of COBRE projects. In addition, the Core will coordinate access to African American families living on barrier islands along the South Carolina Coast ("Sea Islands") and adjacent coastal communities via MUSC's pre-existing Sea Island Families Projects. The specific aims of the Cllinical Resources Core are to: - Provide an outpatient dental clinical research capacity to support all COBRE projects - Collect demographic and other survey data as required by COBRE clinical protocols - Provide calibrated dental examiners for all COBRE clinical investigations - Collect, process, and distribute biological samples for laboratory analysis - Collect, process, and bank biological samples for future studies - Perform specialized biological assays on biological samples, as required by COBRE clinical protocols To perform an oral health assessment of African Americans and Gullah speaking population on the Sea Islands of South Carolina, additional specific aims of the Clinical Resources Core are: - To characterize this unique ethnic population from the oro-dental findings view point - To determine the caries prevalence using caries index (DMFT and dmft) - To determine the presence of periodontal disease - To determine the presence of soft tissue lesions and cancer - To determine the dental treatment needs of this population - To provide oral dental education to the population unde