COBRE: MUSC: CORE C: CLINICAL RESOURCES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 临床资源核心的目标是协调所有COBRE临床活动。临床资源核心将提供必要的临床和实验室专业知识，以促进COBRE项目的实施。此外，核心将协调进入非洲裔美国人家庭生活在屏障岛屿沿着 南卡罗来纳州海岸（“海岛”）和邻近的沿海社区通过MUSC的预先存在的海岛家庭项目。临床资源核心的具体目标是： - 提供门诊牙科临床研究能力，以支持所有COBRE项目 - 根据COBRE临床方案的要求收集人口统计数据和其他调查数据 - 为所有COBRE临床研究提供校准的牙科检查员 - 收集、处理和分发生物样本用于实验室分析 - 收集、处理和储存生物样本以备将来研究之用 - 根据COBRE临床方案的要求，对生物样本进行专门的生物测定 为了对南卡罗来纳州海岛上的非裔美国人和讲Gullah语的人群进行口腔健康评估，临床资源核心的其他具体目标是： - 从口腔-牙科发现的观点来描述这一独特的种族人群 - 用龋指数（DMFT和dmft）测定患龋率 - 确定牙周病的存在 - 确定是否存在软组织病变和癌症 - 确定这一人群的牙科治疗需求 - 为研究对象提供口腔牙科教育

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of the Clinical Resources Core is to coordinate all COBRE clinical activities. The Clinical Resource Core will provide the necessary clinical and laboratory expertise to facilitate the implementation of COBRE projects. In addition, the Core will coordinate access to African American families living on barrier islands along the South Carolina Coast ("Sea Islands") and adjacent coastal communities via MUSC's pre-existing Sea Island Families Projects. The specific aims of the Cllinical Resources Core are to: - Provide an outpatient dental clinical research capacity to support all COBRE projects - Collect demographic and other survey data as required by COBRE clinical protocols - Provide calibrated dental examiners for all COBRE clinical investigations - Collect, process, and distribute biological samples for laboratory analysis - Collect, process, and bank biological samples for future studies - Perform specialized biological assays on biological samples, as required by COBRE clinical protocols To perform an oral health assessment of African Americans and Gullah speaking population on the Sea Islands of South Carolina, additional specific aims of the Clinical Resources Core are: - To characterize this unique ethnic population from the oro-dental findings view point - To determine the caries prevalence using caries index (DMFT and dmft) - To determine the presence of periodontal disease - To determine the presence of soft tissue lesions and cancer - To determine the dental treatment needs of this population - To provide oral dental education to the population under study