Enhancing Prevention for Children in Diverse Populations

描述(申请人提供)：背景和候选人。了解和消除健康方面的差距是国家的优先事项。黑人和拉丁裔儿童背负着不成比例的哮喘负担，这是儿童发病率的主要原因。然而，与白人儿童相比，少数族裔儿童不太可能使用适当的预防性药物。这项申请要求为Tracy Lieu博士，医学博士，公共卫生硕士，国家认可的儿科卫生服务研究员颁发以患者为中心的研究(K24)职业中期研究员奖。刘博士最近成为哈佛大学新成立的儿童保健研究中心的主任。她的目标是加强对儿童，特别是少数族裔儿童采取有效的预防性卫生干预措施。她的记录表明，在资助的哮喘和疫苗研究方面，生产率很高。指导计划。刘博士有越来越多的指导记录和与初级研究人员合作的绝佳机会。她负责她的新中心的三名初级教员，他们都是在他们的头三年。她也是哈佛儿科保健服务研究奖学金计划儿童医院的现场主任。这个K24奖项是为了保护刘博士在指导这些初级研究人员建立他们的研究组合时所花的时间。 研究计划。这项K24奖项中提议的研究建立在Lieu博士正在进行的NICHD支持的R01上，该R01关于患有持续性哮喘的儿童在使用药物方面的种族/民族差异。我们的目标是： 1.进行前瞻性队列研究，以评估父母与提供者的沟通模式和健康信念作为预测黑人、拉丁裔和白人持续哮喘儿童采用预防性药物和接种流感疫苗的指标；以及 2.分析现有数据，以确定实践现场政策以及临床医生和患者层面的预测因素，即在不同的持续性哮喘儿童群体中采用预防性药物。 总结。这个应用程序提供了一个智力丰富的环境中非常成功的研究人员的组合。拟议的奖励将使刘博士能够节省时间指导初级研究人员，并扩大她在改善不同儿童群体的预防性医疗保健方面的研究。对于刘博士和她新中心的初级教员来说，这个K24奖项的支持将在一个关键时刻到来。

DESCRIPTION (provided by applicant): Background and Candidate. Understanding and eliminating disparities in health is a national priority. Black and Latino children bear a disproportionate burden of asthma, a leading cause of childhood morbidity. Yet, minority children are less likely to be using appropriate preventive medications than white children. This application requests a mid-career investigator award in patient-oriented research (K24) for Dr. Tracy Lieu, MD, MPH, a nationally recognized pediatric health services researcher. Dr. Lieu has recently become Director of the new Center for Child Health Care Studies in her department at Harvard. Her goal is to enhance the adoption of effective preventive health interventions for children, especially minority children. Her record demonstrates high productivity in funded research in asthma and vaccines. Mentoring Plan. Dr. Lieu has a growing track record of mentoring and excellent opportunities to work with beginning investigators. She is responsible for three of the junior faculty in her new Center, all of whom are within their first three years. She is also the Children's Hospital Site Director of the Harvard Pediatric Health Services Research Fellowship Program. This K24 award is needed to protect Dr. Lieu's time for guiding these beginning investigators as they establish their research portfolios. Research Plan. The proposed research in this K24 award builds on Dr. Lieu's ongoing NICHD-supported R01 on racial/ethnic disparities in medication use by children with persistent asthma. The aims are to: 1. Conduct a prospective cohort study to evaluate parent-provider communication patterns and health beliefs as predictors of preventive medication adoption and influenza vaccination among black, Latino, and white children with persistent asthma; and 2. Analyze existing data to identify practice site policies as well as clinician and patient-level predictors of preventive medication adoption among a diverse group of children with persistent asthma. Summary. This application offers a combination of a highly successful researcher in an intellectually rich environment. The proposed award will enable Dr. Lieu to protect time for mentoring beginning investigators and expand her research in improving preventive health care for diverse populations of children. Support from this K24 award will come at a critical time for Dr. Lieu and for the junior faculty in her new Center.