Oklahoma Center on American Indian Diabetes Health Disparities

俄克拉荷马州美洲印第安人糖尿病健康差异中心

• 批准号: 7304020
• 负责人: Joseph Neil Henderson
• 金额: $ 114.37万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-30 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7304020
• 关键词: Oklahoma; Center; American; Indian; Diabetes

DESCRIPTION (provided by applicant): The purpose of the Oklahoma Center for American Indian Diabetes Health Disparities (OCAIDHD) is to reduce and eventually eliminate the excess mortality, morbidity, and quality of life and culture lost due to diabetes. The primary impacts of the OCAIDHD will be on diabetes, maternal health, infant mortality, and obesity. The OCAIDHD confronts health disparities by focusing the expertise of a multi-disciplinary, multi-college team of diabetes researchers on specific biological, physiological, behavioral, and cultural stressors of the disease. The Center also has added non-university strengths owing to its partnership with the Oklahoma City Area Inter-tribal Health Board (covering all tribes in Oklahoma, Kansas, and Texas) and its Southern Plains Center on American Indian Epidemiology. That the OCAIDHD is directed by an American Indian (AI) researcher is a significant part of its ability to relate to American Indian people who continue to endure health disparities in the face of unprecedented medical technology for diabetes. The Center is organized by four cores: 1) Administration, 2) Research, 3) Research Training and Education, and 4) Community Engagement and Outreach. The Administrative Core will serve as the overall unit of coordination, supervision, and accounting. It will be directed by the Center PI and have an internal Executive Committee comprised of the PI, Co-Pi, Project Coordinator, and all Core Directors. The Administrative Core will also house the External Advisory Committee comprised of AI diabetes researchers and leaders outside the University. The Research Core will be directed by the Center's Co-PI. The Research Core will oversee three Full Proposals and four Pilot Projects. The cross-cutting theme is reduction of the multiplicative effects of biomedical and sociocultural insults to optimal management of diabetes. Full Proposal topics are 1) Early Markers of Pre-eclampsia in American Indians with Type 2 Diabetes, 2) Insulin Resistance and Glucocorticoid Treatment of Inflammatory Diseases of High Prevalence among AFs, and 3) AI Diabetes Beliefs and Practices: Maternal Care, Infant Mortality, and Adherence. Pilot Projects will explore these topics: 1) SF-36 Medical Outcomes Survey: Validations and Cultural Adaptation in the American Indian Population with Diabetes, 2) Weight Bearing Activity: Links to Diabetic Foot Health in American Indians, 3) Regular Moderate Exercise in Elementary-aged American Indians: Steady Activity in Life Study (SAILS), and 4) Arterial Elasticity in Overweight and Normal Weight American Indian Children. The Research Training/Education Core is directed by an AI who is the head of the Southern Plains Epidemiology Center of the OCAIHD's partner organization. The core's activities will prepare nurses from AI clinics and hospitals in Oklahoma and Kansas with the instruction and support necessary to conduct practical research studies within their health care settings. Completion of this activity will result in a cadre of AI nurse researchers with a specialty in diabetes, a curriculum for model replication, and a process evaluation. This core will also coordinate other education activities of the Center .The Community Engagement/Outreach Core is directed by an AI behavioral science specialist in childhood traumas. This core will augment and support the Native Youth Preventing Diabetes summer camp open to all Oklahoma AI's age 8-12 years. This vital project will expand the number of attendees and collect data on fasting lipids, glucose, blood pressure, random blood glucose, waist circumference, and BMI.

描述(由申请人提供)：俄克拉何马州美国印第安人糖尿病健康差异中心(OCAIDHD)的目的是减少并最终消除因糖尿病而失去的额外死亡率、发病率、生活质量和文化。OCAIDHD的主要影响将是糖尿病、孕产妇健康、婴儿死亡率和肥胖症。OCAIDHD通过将糖尿病研究人员的多学科、多学院团队的专业知识集中在疾病的特定生物、生理、行为和文化应激源上，来应对健康差距。该中心还通过与俄克拉荷马城地区部落间健康委员会(覆盖俄克拉荷马州、堪萨斯州和德克萨斯州的所有部落)及其南方平原美洲印第安人流行病学中心的合作，增加了非大学的优势。OCAIDHD由一名美国印第安人(AI)研究人员指导，这是其与美国印第安人建立联系的能力的重要组成部分，这些人在前所未有的糖尿病医疗技术面前继续忍受着健康差距。该中心由四个核心组成：1)行政，2)研究，3)研究培训和教育，4)社区参与和外展。行政核心将作为协调、监督和核算的整体单位。它将由PI中心领导，并有一个由PI、共同PI、项目协调员和所有核心董事组成的内部执行委员会。行政核心还将容纳由人工智能糖尿病研究人员和大学以外的领导人组成的外部咨询委员会。研究核心将由该中心的合作-PI指导。研究核心将监督三个完整的提案和四个试点项目。交叉主题是减少生物医学和社会文化侮辱对糖尿病最佳管理的倍增影响。完整的提案主题是1)患有2型糖尿病的美国印第安人先兆子痫的早期标志，2)胰岛素抵抗和糖皮质激素治疗急性胰腺炎高发的炎症性疾病，以及3)人工智能糖尿病的信念和实践：产妇护理、婴儿死亡率和坚持。试点项目将探讨以下主题：1)SF-36医疗结果调查：对患有糖尿病的美洲印第安人人群进行验证和文化适应；2)负重活动：与美洲印第安人糖尿病足健康的联系；3)初级美洲印第安人的定期适度运动：稳定的生活活动研究；4)超重和正常体重的美洲印第安人儿童的动脉弹性。研究培训/教育核心由一名人工智能指导，他是OCAIHD合作组织南方平原流行病学中心的负责人。该中心的活动将为俄克拉荷马州和堪萨斯州的人工智能诊所和医院的护士提供必要的指导和支持，以便在他们的医疗保健环境中进行实际研究。完成这项活动将产生一支具有糖尿病专业知识、模型复制课程和过程评估的人工智能护士研究干部队伍。该核心还将协调中心的其他教育活动。社区参与/外联核心由一名儿童创伤方面的人工智能行为科学专家指导。这一核心将加强和支持土著青年预防糖尿病夏令营向所有俄克拉荷马州8-12岁的AI儿童开放。这个重要的项目将扩大与会者的数量，并收集关于空腹血脂、血糖、血压、随机血糖、腰围和BMI的数据。