RT-ISIS: Real-Time In Situ In vivo Surgical Sensing and Imaging

RT-ISIS：实时原位体内手术传感和成像

• 批准号: DT/F003064/1
• 负责人: Guang-Zhong Yang
• 金额: $ 124.68万
• 依托单位: Imperial College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2008
• 资助国家: 英国
• 起止时间: 2008 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=DT%2FF003064%2F1
• 关键词: RT; ISIS; Real; Time; Situ

Recent technological advances in surgery have resulted in a broad range of new techniques for reducing patient trauma, shortening hospitalisation, and improving diagnostic accuracy and therapeutic outcome. RT-ISIS is in response to the current paradigm shift and clinical demand in bringing cellular and molecular imaging modalities to an in vivo / in situ setting to allow for real-time tissue characterisation, functional assessment, and intraoperative guidance. The aim of RT-ISIS is to simultaneously develop and apply new multimodality imaging methods based on excitation/emission spectral resolution suitable for endoscopy and laparoscopy. The project involves significant R&D challenges, and the end results are likely to trans-form clinical research and practices in cancer staging, minimally invasive surgery, interventional imaging, and the development of molecular imaging techniques.

外科手术的最新技术进步带来了广泛的新技术，可减少患者创伤，缩短住院时间，提高诊断准确性和治疗效果。RT-ISIS是为了响应当前的范式转变和临床需求，将细胞和分子成像模式引入体内/原位环境，以实现实时组织表征、功能评估和术中指导。RT-ISIS的目的是同时开发和应用基于激发/发射光谱分辨率的新的多模态成像方法，适用于内窥镜和腹腔镜检查。该项目涉及重大的研发挑战，最终结果可能会改变癌症分期，微创手术，介入成像和分子成像技术发展的临床研究和实践。

项目成果

Affine-invariant anisotropic detector for soft tissue tracking in minimally invasive surgery

• DOI: 10.1109/isbi.2009.5193238
• 发表时间: 2009-06
• 期刊: 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro
• 作者: S. Giannarou;M. V. Scarzanella;Guang-Zhong Yang

Parallel detection of amplitude-modulated, ultrasound-modulated optical signals.

• DOI: 10.1364/ol.35.002633
• 发表时间: 2010-08
• 期刊: Optics letters
• 影响因子: 3.6
• 作者: Rui Li;Lipei Song;D. Elson;M. Tang

Light sources for single-access surgery.

用于单通道手术的光源。

• DOI: 10.1177/1553350611421021
• 发表时间: 2012
• 期刊: Surgical innovation
• 影响因子: 1.5
• 作者: Clancy NT

Spectrally encoded fiber-based structured lighting probe for intraoperative 3D imaging.

• DOI: 10.1364/boe.2.003119
• 发表时间: 2011-11-01
• 期刊: Biomedical optics express
• 影响因子: 3.4
• 作者: Clancy NT;Stoyanov D;Maier-Hein L;Groch A;Yang GZ;Elson DS
• 通讯作者: Elson DS

Medical Imaging and Augmented Reality

医学成像和增强现实

• DOI: 10.1007/978-3-642-15699-1_33
• 发表时间: 2010
• 作者: Giannarou S