EPSRC-NIHR HTC Partnership Award: Technology Network on Devices for Surgery and Rehabilitation

EPSRC-NIHR HTC 合作伙伴奖：手术和康复设备技术网络

• 批准号: EP/M000257/1
• 负责人: Guang-Zhong Yang
• 金额: $ 19.39万
• 依托单位: Imperial College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FM000257%2F1
• 关键词: EPSRC; NIHR; HTC; Partnership; Award

Advances in surgery have made a significant impact on the management of major acute diseases, prolonging life and continuously extending survival rates. Earlier diagnosis, improved efficiency and delivery of therapeutic measures combined with advances in surgical techniques have all contributed to improved prognosis. Many terminal illnesses have now been transformed into clinically manageable, chronic lifelong conditions. Increased longevity and survival after major illness has resulted in many surgical patients being more likely to have co-morbidities; the future of surgery is therefore moving towards precision intervention, increasingly driven by focus on quality-of-life after surgery, as well as the need for taking a systems approach towards surgery. The aim of the proposed network is to establish a forum for surgical innovation with seamless integration of engineering research, clinical translation and industrial development by aligning EPSRC healthcare technologies with NIHR Healthcare Technology Co-operatives (HTCs) to accelerate the development and clinical adoption of new surgical and assistive devices that can improve the treatment, functional restoration, rehabilitation and quality-of-life for patients. The network is supported by two NIHR HTCs - the Enteric HTC led by Barts Health NHS Trust and the Trauma Management HTC by University Hospitals of Birmingham NHS Foundation Trust. The proposed network will also be supported by Health KTN and a number of academic, NHS, industrial and healthcare stakeholders. The research and clinical bases to be covered by the proposed Technology Network will include the following three areas: 1) Sensing for improved peri-operative care - which is a determining factor for mitigating against post-operative complications; 2) Smart surgical devices - for surgery with increased consistency and accuracy, streamlining intraoperative surgical decision making and circumventing potential post-operative complications and revisions; 3) Assistive devices and robots - to facilitate remote monitoring and managed rehabilitation in community or home care settings. The three areas share common engineering research challenges but need to be pursued under different clinical context. The planned activities of the network include 1) Network Events: Symposia and Focused Workshops; 2) Strategic Roadmap events and User Forums; 3) Support for Interdisciplinary Mobility and Industrial Secondment; 4) Proof-of-Concept Projects and Design Competitions; 5) Exhibitions and Patient/Public Engagement; and 6) Online Engagement, Web Forum and Social Media; and 7) Health Policy and High Level Engagement. The benefits for those involved in the proposed network include partnership with extensive industrial and clinical connections already established by the partnering HTCs, host institutions, clinically aligned research and development pathways addressing the future of surgery, engagement of healthcare stakeholders and policy makers, access to research expertise and young talents in this highly interdisciplinary area, early end-user involvement, and tapping into design expertise, access to user group feedback, deliver rapid results through HTCs' clinical network, match evidence to needs of NICE, strong commercial engagement.

外科的进步对重大急性疾病的治疗、延长生命和不断提高生存率产生了重大影响。早期诊断，提高效率和提供治疗措施结合手术技术的进步都有助于改善预后。许多绝症现在已经转变为临床可控制的慢性终身疾病。重大疾病后寿命和生存率的增加导致许多手术患者更有可能患有合并症;因此，手术的未来正朝着精确干预方向发展，越来越多地受到术后生活质量的关注以及对手术采取系统方法的需求的推动。拟议网络的目的是通过将EPSRC医疗保健技术与NIHR医疗保健技术合作社（HTC）对齐，建立一个外科创新论坛，将工程研究，临床翻译和工业发展无缝集成，以加速新的外科和辅助设备的开发和临床采用，从而改善患者的治疗，功能恢复，康复和生活质量。该网络由两个NIHR HTC支持-由Barts Health NHS Trust领导的肠道HTC和伯明翰NHS基金会信托大学医院的创伤管理HTC。拟议的网络还将得到Health KTN和一些学术，NHS，工业和医疗保健利益相关者的支持。拟议的技术网络将涵盖的研究和临床基础将包括以下三个领域：1）用于改善围手术期护理的传感-这是减轻术后并发症的决定性因素; 2）智能手术设备-用于提高一致性和准确性的手术，简化术中手术决策并避免潜在的术后并发症和翻修; 3）辅助设备和机器人-促进社区或家庭护理环境中的远程监控和管理康复。这三个领域有着共同的工程研究挑战，但需要在不同的临床背景下进行。该网络计划的活动包括：1）网络活动：研讨会和重点研讨会; 2）战略路线图活动和用户论坛; 3）支持跨学科流动和行业借调; 4）概念验证项目和设计竞赛; 5）展览和患者/公众参与; 6）在线参与，网络论坛和社交媒体; 7）卫生政策和高级别参与。参与拟议网络的人的好处包括与合作HTC已经建立的广泛的工业和临床联系的伙伴关系，主办机构，临床对齐的研究和开发途径，解决外科手术的未来，医疗保健利益相关者和政策制定者的参与，在这个高度跨学科的领域获得研究专业知识和年轻人才，早期最终用户参与，利用设计专业知识，获得用户群体反馈，通过HTC的临床网络提供快速结果，将证据与NICE的需求相匹配，强大的商业参与。

项目成果

Disparity in Frontal Lobe Connectivity on a Complex Bimanual Motor Task Aids in Classification of Operator Skill Level

• DOI: 10.1089/brain.2015.0350
• 发表时间: 2016-06-01
• 期刊: BRAIN CONNECTIVITY
• 影响因子: 3.4
• 作者: Andreu-Perez, Javier;Leff, Daniel Richard;Yang, Guang-Zhong
• 通讯作者: Yang, Guang-Zhong

Constrained Statistical Modelling of Knee Flexion From Multi-Pose Magnetic Resonance Imaging.

多姿势磁共振成像膝关节屈曲的约束统计模型。

• DOI: 10.1109/tmi.2016.2524587
• 发表时间: 2016
• 期刊: IEEE transactions on medical imaging
• 影响因子: 10.6
• 作者: Constantinescu MA

Evaluation of neurosurgical innovation using patent database.

使用专利数据库评估神经外科创新。

• DOI: 10.3171/2015.8.jns151854
• 发表时间: 2016
• 期刊: Journal of neurosurgery
• 影响因子: 4.1
• 作者: Amadio JP

Editorial: big data for health.

社论：健康大数据。

• DOI: 10.1109/jbhi.2015.2442392
• 发表时间: 2015
• 期刊: IEEE journal of biomedical and health informatics
• 影响因子: 7.7
• 作者: Atun R

Best of Bodynets 2014: Editorial

2014 年最佳 Bodynets：社论

• DOI: 10.1109/taffc.2016.2595418
• 发表时间: 2016
• 期刊: IEEE Transactions on Affective Computing
• 影响因子: 11.2
• 作者: Fortino G