Physician Scientist Research Training in Pathogenesis of Viral Diseases

病毒性疾病发病机制的医师科学家研究培训

• 批准号: 7467384
• 负责人: Mary E. Klotman
• 金额: $ 4.89万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7467384
• 关键词: Pathogenesis; Physicians; Research Training; Scientist; Virus Diseases

DESCRIPTION (provided by applicant): Viral diseases continue to be a major threat to both the pediatric as well as the adult patient population. In recent years, the rapid emergence and spread of relatively new human pathogens such as HIV and SARS, the increasing morbidity and mortality associated with persistent and prolonged infection with agents such as Hepatitis C as well as the episodic and often unexplained reemergence of pathogens underscores the necessity of having well trained investigators that can respond rapidly to these public health demands. The goal of this research training grant is to prepare physicians (MD and MD/PhDs) to pursue careers as independent investigators specifically in the area of viral pathogenesis with a primary focus on virus/host interactions. Each of the twelve faculty members representing the key training personnel for this program has a strong track record in the area of viral pathogenesis as reflected in both publications as well as funding and a commitment to training physician-scientists. Each plays a major role in the graduate school as well as their respective departments and has developed extensive collaborative interactions which will provide the trainee a critical and accessible network of expertise. The institutional commitment in this area is reflected by the recent creation of the Emerging Infections Center that will allow continued recruitment of outstanding faculty to reflect Mt. Sinai and will provide an additional framework for trainees to benefit from the interdisciplinary nature of research in this arena. The training program is designed to extend the training period of physicians following completion of their clinical fellowships, particularly in Adult and Pediatric Infectious Diseases. The candidates will enter into their research training track in their second year of fellowship and will be candidates for funding through the training grant for two subsequent years. The major activity (representing 90% of their time) during these two years will be mentored laboratory investigation on an individual project. This experience will be complemented by participation in a weekly journal club, weekly laboratory data sessions as well as divisional, departmental, and institutional research conferences. The goal of this program is to provide the candidate with the necessary skills and training to effectively compete for mentored scientist awards as the next step in their transition to independent careers as physician scientists.

描述（由申请人提供）：病毒性疾病仍然是儿科和成人患者群体的主要威胁。近年来，艾滋病毒和非典型肺炎等相对较新的人类病原体的迅速出现和传播，与丙型肝炎等病原体持续和长期感染相关的发病率和死亡率不断上升，以及病原体的偶发性且常常无法解释的重新出现，都强调了拥有训练有素的调查人员能够对这些公共卫生需求做出快速反应的必要性。这项研究培训拨款的目标是帮助医生（医学博士和医学博士/博士）做好准备，成为独立研究人员，特别是在病毒发病机制领域，主要关注病毒/宿主相互作用。代表该项目关键培训人员的十二名教员中的每一位都在病毒发病机制领域拥有良好的记录，这在出版物、资金和对培训医师科学家的承诺中都得到了反映。每个人都在研究生院及其各自的部门中发挥着重要作用，并发展了广泛的协作互动，这将为学员提供关键且可访问的专业知识网络。最近成立的新发感染中心反映了该领域的机构承诺，该中心将允许继续招募优秀教师以反映西奈山的情况，并将为学员提供一个额外的框架，让他们从该领域的跨学科研究中受益。该培训计划旨在延长完成临床奖学金后医生的培训期限，特别是在成人和儿童传染病领域。候选人将在奖学金的第二年进入研究培训轨道，并将成为通过随后两年的培训补助金资助的候选人。这两年的主要活动（占他们 90% 的时间）将是对单个项目的实验室调查进行指导。这种经验将通过参加每周的期刊俱乐部、每周的实验室数据会议以及部门、部门和机构研究会议得到补充。该计划的目标是为候选人提供必要的技能和培训，以有效竞争指导科学家奖项，作为他们向医师科学家独立职业过渡的下一步。