Mathematical Models and Experimental Microbial Systems: Tools for Studying Evolution

数学模型和实验微生物系统：研究进化的工具

• 批准号: EP/D069408/1
• 负责人: Nicholas Britton
• 金额: $ 1.23万
• 依托单位: University of Bath
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2007
• 资助国家: 英国
• 起止时间: 2007 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FD069408%2F1
• 关键词: Mathematical; Models; Experimental; Microbial; Systems

The goal of the proposed workshop is to bring together mathematicians and life scientists to discuss challenges and explore solutions to some of the major problems in evolutionary ecology. In particular the workshop will focus around two questions that have been highlighted in a recent issue of Science: What determines species diversity? How did cooperative behaviour evolve? It was acknowledged that the advancement of our understanding of the issues relating to these questions will require a major interdisciplinary effort involving interactions between mathematical and biological communities.One way of approaching the above problems is to perform laboratory experiments where evolution can be observed as it happens and where good quality data at the genetic level can be obtained. There has been a recent explosion of such studies using micro-organism that include bacteria, viruses, yeast and some slime moulds. At the same time numerous mathematical models of evolution are being developed, important predictions are being made but it is still rare that the models are tested and refined through being fully challenged by data.Holding a workshop that will bring together biological and mathematical communities would therefore be extremely important and timely.The proposed 3 day workshop to be held at the University of Bath in January 2007 is the first step of a wider research plan that involves the creation of an interdisciplinary network aimed at bridging the gap between the two communities and forging links that will lead to long-term collaborations.

拟议的研讨会的目标是汇集数学家和生命科学家讨论挑战，并探索解决进化生态学中一些主要问题的方法。特别是，研讨会将重点围绕最近一期《科学》杂志上强调的两个问题：是什么决定了物种多样性？合作行为是如何进化的？人们认识到，要想提高对这些问题的认识，就需要数学界和生物界进行跨学科的努力，解决上述问题的一种方法是进行实验室实验，在实验室里可以观察到进化的发生，并可以获得高质量的遗传数据。最近，利用细菌、病毒、酵母和一些黏菌等微生物进行的此类研究激增。与此同时，许多进化的数学模型正在开发中，重要的预测正在进行，但通过数据的充分挑战来测试和改进模型的情况仍然很少。因此，举办一个将生物学和数学界聚集在一起的研讨会是非常重要和及时的。拟议于2007年1月在巴斯大学举行的为期3天的研讨会是第一个这是一个更广泛的研究计划的一个步骤，涉及建立一个跨学科网络，旨在弥合两个社区之间的差距，并建立将导致长期合作的联系。