Admin. Core Interdepartmental Two-photon Imaging Center

行政。

• 批准号: 7408917
• 负责人: DALTON JAMES SURMEIER
• 金额: $ 30.23万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2011-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7408917
• 关键词: Adhesions; Annual Reports; Biological; Biological Sciences; Cells; Charge; Chicago; Educational process of instructing; Engineering; Equipment; Equipment and Supplies; Equipment and supply inventories; Faculty; Germany; Graduate Education; Image; Image Analysis; International; Life; Mediation; Microscopy; Neurons; Optics; Participant; Pediatric Neurology; Phototoxicity; Physiology; Policies; Price; Resources; Role; Running; Schedule; Seminal; Signal Transduction; Societies; Source; Students; System; United States National Institutes of Health; Universities; Vendor; base; day; driving force; migration; symposium; theories; two-photon

The administration of the Center Core will be distributed into three parts: Administrative Core, Imaging Cores, and a Steering Committee. The Administrative Core will be managed by a Core Advisor who will be assisted by an administrative staff (see Chart on next page). The Core Advisor (22% effort) will be in charge of equipment purchases and negotiating prices with vendors (especially where multiple purchases may enable price reductions), managing the administrative staff, maintaining an inventory of core equipment and supplies, scheduling regular meetings of the Steering Committee, and serving as liaison between the Steering Committee and the Core Directors. He will also be responsible for overseeing the system improvement projects, coordinating activities with our corporate partner and consultants, and organizing and completing the annual reports to NIH. Dr. Hockberger, Director of the 2P Imaging Cores in Physiology and consultant on the 2P cores in Pediatrics and Neurology, has agreed to serve as the Core Advisor. He has been active in the field of optical physiology for 25 years, and he has made seminal contributions related to dendritic Ca2+ signaling, the role of differential adhesion in neuronal migration and pathfinding, and the sources and remedies of phototoxicity during live cell microscopy. He has been responsible for developing imaging resources (including CCD-based and 2P imaging) at NU, Loyola University (Chicago), University of Erlangen (Germany), and the University of Bonn (Germany). He has been an active participant in the International Society for Optical Engineers (SPIE) for the past 12 yrs, and he has been an invited speaker at numerous national and international symposia. At NU, he has taken a leading role in the education of graduate students and postdocs on the quantitative aspects of biological imaging. Since 1992, he has directed a graduate course (IGP 415: Biological Imaging: Principles and Applications) that teaches the theory and practice of quantitative image analysis in the life sciences. Each imaging core will be managed by a Core Director. We have identified appropriate faculty who have agreed to serve as Core Directors (see Chart), and their effort (5%) will be contributed by their respective departments. Directors will be responsible for oversight of the core, advising users on policies within the core, and keeping track of core usage. Each Director will have technical support to assist in running the day to day activities of the core (see Technical support, below). Oversight of the Center Core will be the responsibility of a Steering Committee comprised of the PI, senior faculty representing the various departments involved in this proposal, and the Core Advisor (ex officio). Dr. Surmeier (PI) has been the driving force behind the creation of the 2P imaging cores in

中心核心的管理将分为三个部分：管理核心、成像 核心，以及一个指导委员会。行政核心将由一名核心顾问管理，该顾问将 由行政人员协助(见下一页图表)。核心顾问(22%的工作)将负责 设备采购和与供应商协商价格(特别是在多个采购可能实现的情况下 降价)、管理行政人员、维护核心设备库存以及 供应，安排指导委员会的定期会议，并担任指导委员会之间的联络 委员会和核心董事。他还将负责监督系统改进项目， 与公司合作伙伴和顾问协调活动，并组织和完成 向美国国立卫生研究院提交年度报告。 Hockberger博士，生理学2P成像核心主任兼儿科2P核心顾问 和神经科，已经同意担任核心顾问。他一直活跃在光学生理学领域 25年来，他在树突状细胞钙信号转导、分化作用等方面做出了开创性的贡献 神经细胞迁移和寻路中的黏附以及活体期间光毒性的来源和补救 细胞显微镜。他一直负责开发成像资源(包括基于CCD的和2P 成像)、洛约拉大学(芝加哥)、埃尔兰根大学(德国)和波恩大学 (德国)。他一直是国际光学工程师协会(SPIE)的积极参与者 在过去的12年里，他一直是许多国内和国际研讨会的特邀演讲者。在NU，他 在研究生和博士后数量方面的教育中发挥了主导作用 生物成像。自1992年以来，他指导了一门研究生课程(IGP 415：生物成像：原理和 应用)，教授生命科学中定量图像分析的理论和实践。 每个成像核心将由一名核心总监管理。我们已经确定了合适的教职员工 同意担任核心董事(见图表)，他们的努力(5%)将由各自的部门贡献。 董事将负责监督核心，就核心内的政策向用户提供建议， 并跟踪核心使用情况。每个主管都将得到技术支持，协助日常运作 核心活动(见下文的技术支持)。 对中心核心的监督将由一个由PI组成的指导委员会负责， 代表本提案涉及的各个部门的高级教职员工和核心顾问 (当然)。Surmeier博士(Pi)一直是创建2P成像核心的幕后推手