A Versatile new family of highly luminescent platinum complexes: application from OLEDs to chemical sensors

多功能新系列高发光铂配合物：从 OLED 到化学传感器的应用

• 批准号: EP/D500265/1
• 负责人: JAG Williams
• 金额: $ 18.77万
• 依托单位: Durham University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FD500265%2F1
• 关键词: Versatile; new; family; highly; luminescent

The research will explore applications of a new family of compounds containing platinum bound to NACANcoordinating ligands. By NAC^N, we mean an organic molecule that coordinates to the metal through two nitrogens and a central metal-carbon bond. The compounds are luminescent - they emit light when electrical or light energy is applied - and the short length of the Pt-C bond in our compounds makes the emission exceptionally bright. The objective of the research will be to put this bright emission to good use in two technologically important applications:(A). Organic light-emitting devices (OLEDs).Widely expected to be the next generation of display screen technology, OLEDs make use of small organic molecules or conjugated polymers, and offer advantages over existing LED technology; e.g. they can be formed as thin flexible plastics, so that TV screens could even be made by ink-jet printing. However, only a minority of the excited states that are formed when electrical charge is applied can emit light, namely the spin-paired singlet states. Luminescent heavy metal complexes are required to induce emission from the normally non-emissive triplet states (with electron spins parallel). We shall explore new NAC^N -coordinated platinum complexes for this purpose. They are likely to be very suitable for this application, because of their high efficiency of emission, charge-neutrality, ease of preparation, and amenability to derivatisation allowing a family of closely-related complexes with different colours of emission to be obtained. We will examine the effect of the fourth ligand on the stability and properties of the complexes, as well as working on other ligands offering NACAN coordination. A new strategy for tackling the problem of decreasing efficiency at high electrical currents will also be investigated, to allow brighter displays to be obtained.(B). A new ratiometric sensor for zinc ions.We will prepare a Pt(NAC^N) complex which incorporates a binding site for zinc ions on its back. The binding site to be considered will be a dipicolylanilino group, which is known to bind to Zn(II) with good selectivity over other metal ions under physiologically relevant conditions. We have discovered that the parent complexes can diffuse across cell membranes very rapidly and show no short-term cytotoxicity, making the Pt(NAC^N) unit attractive as the light-emitting component of a cellullar sensor. The new compounds will offer distinct advantages over currently available sensors for zinc, since they will allow time-resolved measurements to be made, offering greater sensitivity through discrimination from background fluorescence.

这项研究将探索一类新的含铂化合物家族的应用，这些化合物结合到NACAN配位配体上。我们所说的NaC^N是指通过两个氮和一个中心金属-碳键与金属配位的有机分子。这些化合物是发光的--当施加电能或光能时，它们会发光--而我们化合物中的铂-碳键很短，使得发射异常明亮。这项研究的目标将是将这种明亮的发射很好地用于两个重要的技术应用：(A)。有机发光器件(OLED)。有机发光器件(OLED)被广泛认为是下一代显示屏技术，它利用有机小分子或共轭聚合物，比现有的LED技术具有优势；例如，它们可以制成薄薄的柔性塑料，因此甚至可以通过喷墨打印来制造电视屏幕。然而，当施加电荷时，只有一小部分激发态可以发光，即自旋配对的单重态。发光的重金属络合物需要从通常不发射的三重态(电子自旋平行)诱导发射。为此，我们将探索新的NaC^N配位的铂配合物。它们很可能非常适合这一应用，因为它们的发射效率高，电荷中性，易于制备，并且易于衍生化，从而可以获得一系列密切相关的不同发射颜色的络合物。我们将研究第四个配体对络合物稳定性和性质的影响，以及其他提供NACAN配位的配体。还将研究一种新的战略，以解决在高电流情况下效率下降的问题，以便获得更明亮的显示器。一种新型的锌离子比率传感器。我们将制备一种铂(NaC^N)络合物，它的背面含有锌离子的结合部位。考虑的结合部位将是一个二皮酚基苯胺基，在生理条件下，它与锌(II)的结合比其他金属离子有很好的选择性。我们已经发现，母体络合物可以非常迅速地扩散到细胞膜上，并且没有短期的细胞毒性，这使得铂(NaC^N)单元作为细胞传感器的发光元件具有吸引力。与目前可用的锌传感器相比，新化合物将提供明显的优势，因为它们将允许进行时间分辨测量，通过与背景荧光的区分提供更高的灵敏度。