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Role of Sprouty in the Regulation of Renal Development and Cystic Disease

Role of Sprouty in the Regulation of Renal Development and Cystic Disease
芽苗在调节肾脏发育和囊性疾病中的作用
批准号：
7499416
负责人：
PATRICIA D. WILSON
金额：
$13.14万
依托单位：
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
已结题
起止时间：
2007-08-01 至 2008-07-31
来源：
https://reporter.nih.gov/project-details/7499416
关键词：
1-Phosphatidylinositol 3-KinaseAbnormal CellAccountingAnimalsApicalAttentionAutosomal Dominant Polycystic KidneyAutosomal Recessive Polycystic KidneyBehaviorBiological ModelsCell LineCell ProliferationCellsChildChildhoodCystDataDevelopmentDiseaseDisease ProgressionDisruptionDockingDown-RegulationDuct (organ) structureEGF geneEnd stage renal failureEnzyme ActivationEpidermal Growth Factor ReceptorEpithelialEpithelial CellsEventExhibitsHealthHumanIn VitroIncidenceInterventionKidneyKidney FailureKnowledgeLaboratoriesLateralLifeLigandsLiquid substanceMediatingMembraneMitogen-Activated Protein KinasesMorphogenesisMusNewborn InfantNormal CellPathogenesisPathway interactionsPatientsPharmaceutical PreparationsPhenotypePhosphotransferasesPopulationProtein DephosphorylationProtein Kinase CProtein Tyrosine PhosphataseProteinsReceptor ActivationReceptor InhibitionRegulationRegulatory PathwayResearch PersonnelRoleSignal PathwaySignal TransductionStagingStructureTestingTherapeuticTimeTubular formationWorkapical membranebasebasolateral membranecell behaviorin vivoinsightmortalitymouse modelneonateprogramsreceptorreceptor functionreceptor internalizationrenal epitheliumresearch studyresponsesolutetherapy development

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