EXPERIMENTALLY GUIDED RIBOSOMAL RNA MODELING

实验引导的核糖体 RNA 建模

• 批准号: 7386629
• 负责人: JOACHIM FRANK
• 金额: $ 15.67万
• 依托单位: WADSWORTH CENTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-01-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7386629
• 关键词: Amino Acids; Antibiotics; Anticodon; Authorization documentation; Binding; Biochemistry; Cell Line; Cities; Collaborations; Collection; Complex; Computational Technique; Cryoelectron Microscopy; DNA Sequence Rearrangement; Data Collection; Data Set; Disclosure; Doctor of Philosophy; EEF1A1 gene; Event; Face; Florida; Funding; Genetic; Goals; Grant; Guanosine Diphosphate; Guanosine Triphosphate Phosphohydrolases; Hand; Human Resources; Illinois; Imagery; Instruction; Kinetics; Last Name; Ligands; Maps; Messenger RNA; Modeling; Molecular; Molecular Conformation; Molecular Models; Motion; Names; New York; Numbers; Organelles; Other Finding; Peptide Elongation Factor G; Peptide Elongation Factor Tu; Performance; Positioning Attribute; Principal Investigator; Printing; Process; Prokaryotic Cells; Proteins; Public Health; RNA; Range; Registries; Research; Research Project Grants; Resolution; Ribosomes; Roentgen Rays; Role; Site; Staging; Structure; Techniques; Thiostrepton; Time; Transfer RNA; Translating; Translations; USA Georgia; Universities; Western Asia Georgia; Work; X-Ray Crystallography; analog; base; density; human EEF1A1 protein; human embryonic stem cell; improved; knowledge base; molecular dynamics; molecular modeling; mouse Gdi2 protein; mutant; particle; polypeptide; programs; reconstruction; scaffold; single-molecule FRET; tool

The ribosome, as the site where genetic information is translated into polypeptides which subsequently fold into proteins, and as the target site for antibiotic action, is an organelle with eminent

核糖体是遗传信息翻译成多肽的场所， 蛋白质，并作为抗生素作用的靶点，是一种具有显著