AKU Global Network Research Unit

描述（由申请人提供）：5年前，阿拉巴马大学伯明翰分校（DAB）和巴基斯坦卡拉奇的阿迦汗大学（AKU）在全球网络（GN）内竞争并获得了一个研究单位，重点是改善感染相关的围产期发病率和死亡率。尽管经历了几次挫折，UAB/AKU合作项目已经发展成为一个运作良好、富有成效的研究和培训项目。这一更新申请旨在维持和加强全球网络研究股（GNRU）的重点，即改善发展中国家母婴健康，特别强调降低围产期发病率和死亡率。与以前一样，这个GNRU将是UAB妇产科系和AKU社区卫生科学系之间的合作伙伴关系。在巴基斯坦进行的临床研究对象将包括来自城市和农村的孕妇，以及医院和社区的人口。通过这项研究和我们参与的其他共同协议，我们希望促进巴基斯坦研究人员的发展和成长，促进AKU研究人员与UAB研究人员之间的合作。我们还打算通过系统地指导有前途的初级研究人员和从相关领域招募资深科学家，吸引新的美国和巴基斯坦研究人员进入国际妇幼保健研究领域。通过这一切，我们希望通过提供高质量的行政、统计和研究支持服务，在一个科学激励的多学科环境中，改善AKU科学家的研究环境。随着这些多中心项目的完成，我们不仅回答了与发展中国家怀孕和新生儿结局相关的一些非常重要的问题，而且AKU与UAB合作，将开发出一流的农村和城市围产期相关研究基础设施，与他们发展中的妇幼保健系统紧密相连。

DESCRIPTION (provided by applicant): With a focus on improving infection-related perinatal morbidity and mortality, 5 years ago, the University of Alabama at Birmingham (DAB) and the Aga Khan University (AKU), in Karachi, Pakistan competed for and were awarded a Research Unit within the Global Network (GN). Despite several setbacks, the UAB/AKU Collaboration has evolved into a very well-functioning and highly productive research and training program. This renewal application seeks to maintain and enhance that Global Network Research Unit (GNRU) focusing on improving developing country maternal-infant health with a specific emphasis on reducing perinatal morbidity and mortality. This GNRU will be, as before, a partnership between The Dept of OBGYN at UAB and the Dept of Community Health Sciences at AKU. The clinical subjects for studies conducted in Pakistan will include pregnant women from both urban and rural, and hospital and community-based populations. Through this study and our participation in other common protocols, we hope to stimulate the development and growth of Pakistani researchers and promote collaborations between AKU researchers and those from UAB. We also intend to attract new U.S. and Pakistani investigators to the field of international Maternal and Child Health research by systematic mentoring of promising junior investigators and recruiting senior scientists from related fields. In doing all this, we hope to enhance the research environment available to AKU scientists by providing high quality responsive administrative, statistical and research support services within a scientifically stimulating multidisciplinary setting. With the completion of these multi-centered projects, not only will we have answered some very important questions related to pregnancy and newborn outcomes in developing countries, but AKU, in partnership with UAB, will have developed a superb rural and urban perinatal-related research infrastructure, tightly linked to their developing maternal and child health care systems.