Columbia University/Aga Khan University Global Network Research Unit

哥伦比亚大学/阿迦汗大学全球网络研究中心

• 批准号: 9301625
• 负责人: ROBERT L GOLDENBERG
• 金额: $ 65.45万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-30 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9301625
• 关键词: Age; Award; Birth; Caring; Cellular Phone; Cessation of life; Child; Child health care; Childhood; Clinics and Hospitals; Cluster randomized trial; Collaborations; Communities; Community Health; Data; Data Collection; Data Quality; Developing Countries; Enrollment; Environment; Feedback; Fetal Mortality Statistics; Foundations; Funding; Goals; Grant; Growth and Development function; Health; Health Sciences; Hospitals; Industry; Infant; Institution; International; Intervention; Intervention Studies; Intervention Trial; Leadership; Manuscripts; Maternal Mortality; Maternal and Child Health; Mentors; Mission; Morbidity - disease rate; Mothers; Multicenter Trials; Neonatal Mortality; Newborn Infant; Outcome; Pakistan; Participant; Performance; Perinatal; Population; Pregnancy Outcome; Pregnant Women; Preparation; Protocols documentation; Quality of Care; Recruitment Activity; Registries; Research; Research Design; Research Personnel; Research Support; Resources; Rural; Rural Population; Senior Scientist; Services; Site; Sum; System; Universities; Urban Hospitals; Urban Population; Woman; Women' s Health; base; follow-up; improved; intrapartum; low and middle-income countries; mortality; multidisciplinary; neonatal death; population based; programs; protocol development; public health relevance; quality assurance; randomized trial; research study; stillbirth; urban children

DESCRIPTION (provided by applicant): This application to the Global Network (GN) for Women's and Children's Research asks for the Global Network Research Unit of Aga Khan and Columbia Universities to be renewed for a third 5 year term. We believe that our track record, especially over the last 5 years, as documented in the full application, justifies an award for the next 5 years. The strengths of this application include a stable and highly productive team devoted to carrying out meaningful research to improve the health of women and children, large and varied populations for study, and an ongoing birth outcomes registry of 20 rural clusters of 500 deliveries per year each with excellent follow up. Pakistan, with a population of 180,000,000 people and some of the highest maternal, fetal and neonatal mortality rates anywhere in the world, provides every type of population that could be considered for GN studies. We have the largest number of rural clusters of any site in the GN with an active birth registry in each, and have also demonstrated access to a number of urban hospitals for deliveries and access to urban children for research purposes as well. To date we have recruited more than 220,000 subjects for GN studies. In the next 5 years, we plan to bring substantial external resources to the GN by building strong relationships between industry, foundations and the GN to do research meaningful to all three institutions. We will actively participate in the deliberations of the GN Steering Committee and continue to mentor more junior investigators at our site and other sites in the GN in research study design, and manuscript and grant preparation. One of our major goals is to improve facility performance in the care of mothers and infants. Our proposed common protocol alms to reduce facility fetal and neonatal mortality using a defined outcome related to facility care, e.g., the sum of intrapartum stillbirths and early (pre- discharg) neonatal deaths. Using a simple cellular telephone-based data collection system, rapid feedback on the defined outcome, and a quality assurance program aimed at reducing intrapartum related deaths; it is our hope to achieve a substantial improvement in facility-based pregnancy outcomes.

描述（由申请人提供）：本向妇女和儿童研究全球网络 (GN) 提出的申请要求阿迦汗和哥伦比亚大学全球网络研究单位续签第三个 5 年任期。我们相信，我们的业绩记录，尤其是过去 5 年的业绩记录，正如完整申请中所记录的那样，证明了该奖项的合理性 未来5年。该应用程序的优势包括一支稳定且高效的团队，致力于开展有意义的研究，以改善妇女和儿童的健康，研究对象庞大且多样化，并且持续进行出生结果登记，每年有 20 个农村集群，每个集群每年 500 例分娩，并有良好的随访。巴基斯坦拥有 180,000,000 人口，孕产妇、胎儿和新生儿死亡率是世界上最高的，提供了可考虑进行 GN 研究的所有类型的人口。我们拥有北领地所有地区中数量最多的农村集群，每个集群都有活跃的出生登记，并且还可以进入一些城市医院进行分娩，并可以进入城市儿童进行研究。迄今为止，我们已招募了超过 220,000 名受试者进行 GN 研究。未来 5 年，我们计划通过在行业、基金会和 GN 之间建立牢固的关系，为 GN 带来大量外部资源，开展对所有三个机构都有意义的研究。我们将积极参与审议 GN 指导委员会，并继续指导我们站点和 GN 其他站点的更多初级研究人员进行研究设计、手稿和拨款准备。我们的主要目标之一是提高设施在母亲和婴儿护理方面的表现。我们提出的通用方案旨在使用与设施护理相关的明确结果（例如产时死产和早期（出院前）新生儿死亡总数）来降低设施胎儿和新生儿死亡率。使用简单的基于蜂窝电话的数据收集系统，对既定结果进行快速反馈，以及旨在减少产时相关死亡的质量保证计划；我们希望显着改善设施内的妊娠结局。

项目成果

Urogenital fistula reviewed: a marker of severe maternal morbidity and an indicator of the quality of maternal healthcare delivery.

• DOI: 10.1186/s40748-015-0020-7
• 发表时间: 2015
• 期刊: Maternal health, neonatology and perinatology
• 作者: Harrison MS;Mabeya H;Goldenberg RL;McClure EM
• 通讯作者: McClure EM

It Takes a System: Magnesium Sulfate for Prevention of Eclampsia in a Resource-Limited Community Setting.

它需要一个系统：硫酸镁在资源有限的社区环境中预防子痫。

• DOI: 10.9745/ghsp-d-19-00261
• 发表时间: 2019
• 期刊: Global health, science and practice
• 作者: Goldenberg,RobertL;McClure,ElizabethM
• 通讯作者: McClure,ElizabethM

Web-Based Quality Assurance Process Drives Improvements in Obstetric Ultrasound in 5 Low- and Middle-Income Countries.

• DOI: 10.9745/ghsp-d-16-00156
• 发表时间: 2016-12-23
• 期刊: Global health, science and practice
• 作者: Swanson JO;Plotner D;Franklin HL;Swanson DL;Lokomba Bolamba V;Lokangaka A;Sayury Pineda I;Figueroa L;Garces A;Muyodi D;Esamai F;Kanaiza N;Mirza W;Naqvi F;Saleem S;Mwenechanya M;Chiwila M;Hamsumonde D;McClure EM;Goldenberg RL;Nathan RO
• 通讯作者: Nathan RO

Monitoring of birth registry coverage and data quality utilizing lot quality assurance sampling methodology: A pilot study.

利用批次质量保证抽样方法监测出生登记覆盖率和数据质量：一项试点研究。

• DOI: 10.4103/jfmpc.jfmpc_59_17
• 发表时间: 2018
• 期刊: Journal of family medicine and primary care
• 影响因子: 1.4
• 作者: Tikmani,ShiyamSunder;Saleem,Sarah;McClure,Elizabeth;Naqvi,FarnazZehra;Abrejo,Farina;Soomro,Zahid;Wallace,Dennis;Goldenberg,RobertL
• 通讯作者: Goldenberg,RobertL

Cesarean section in sub-Saharan Africa.

• DOI: 10.1186/s40748-016-0033-x
• 发表时间: 2016-01-01
• 期刊: Maternal health, neonatology and perinatology
• 作者: Harrison, Margo S;Goldenberg, Robert L
• 通讯作者: Goldenberg, Robert L