Clinical Outcomes Research: An Endoscopic Data Base

临床结果研究：内窥镜数据库

• 批准号: 7491075
• 负责人: DAVID A LIEBERMAN
• 金额: $ 72.2万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7491075
• 关键词: Adult; Anesthesia procedures; Applications Grants; Area; Attitude; Barrett Esophagus; Characteristics; Childhood; Clinical; Clinical Investigator; Clinical Research; Clinical effectiveness; Collaborations; Collection; Colonic Neoplasms; Communities; Community Practice; Computers; Daily; Data; Data Analyses; Data Files; Databases; Diagnosis; Diagnostic; Digestive System Disorders; Discipline; Disease; Effectiveness; Endoscopy; Ensure; Foundations; Funding; Gastroenterology; Gastrointestinal Diseases; Goals; Health Care Costs; Intervention; Knowledge; Measurement; Measures; Medical; Medical Surveillance; Methods; National Institute of Diabetes and Digestive and Kidney Diseases; Operative Surgical Procedures; Outcome; Outcome Study; Outcomes Research; Pathology; Patients; Pattern; Physicians; Play; Procedures; Propofol; Prospective Studies; Publishing; Quality Control; Quality of Care; Range; Recruitment Activity; Reflux; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Role; Scientific Advances and Accomplishments; Site; Source; Therapeutic Intervention; Time; Translating; Translations; Ulcerative Colitis; United States; Variant; Work; base; capsule; computerized; data integrity; improved; innovation; pressure; programs; prospective; repository; research study; research to practice; success; tool

DESCRIPTION (PROVIDED BY APPLICANT): Pressure to improve the quality and lower the cost of health care has created the need to understand the effectiveness of medical interventions in clinical practice settings. Endoscopy plays an n important role in the diagnosis and management of digestive diseases. Despite widespread use of endoscopy, little is known about outcomes in community-based settings. We developed a practice-based consortium to study endoscopic outcomes. Practice sites utilize a computerized endoscopic report generator to produce endoscopy reports, while simultaneously creating a data file. De-identified endoscopy data is transmitted electronically from sites to a central data repository for data analysis. Quality control measures ensure data integrity and accuracy. The practice consortium now includes 648 physicians in 68 adult, and 11 pediatric practice sites in 28 states. Of all adult endoscopy results, 65 % come from non-academic settings. We have demonstrated successful completion of prospective research projects. In the current proposal, we will build on the foundation of our clinical practice network, to conduct research, which will improve the quality of clinical practice in gastroenterology. The specific themes of this proposal are: Theme 1: Analysis of practice. We will conduct prospective analysis of endoscopic utilization, measure endoscopic findings and complications, practice variation, and identify association, which predict likelihood of favorable or unfavorable outcomes. Theme 2: Translation of research into practice. We will conduct research projects to translate new information about endoscopic outcomes into clinical practice. The consortium provides a unique opportunity to determine hoe new discovery impacts practice. Theme 3: Prospective research. Prospective research will focus on areas of clinical practice that lack critical evidence of effectiveness. We have developed methods for collection of prospective data in the flow of practice, following patient outcomes over time, and measuring changes in practice over time. Theme 4: Provide a resource to the scientific community. We have demonstrated successful collaboration with a wide range of clinical investigators to develop projects that are uniquely suited to a large community-based practice network.

描述(由申请人提供)： 提高卫生保健质量和降低卫生保健成本的压力促使人们有必要了解医疗干预在临床实践环境中的有效性。胃镜检查在消化系统疾病的诊断和治疗中起着重要作用。尽管内窥镜检查被广泛使用，但人们对社区环境下的结果知之甚少。我们开发了一个以实践为基础的联盟来研究内窥镜检查的结果。实习地点利用计算机化的内窥镜报告生成器来产生内窥镜报告，同时创建数据文件。将未识别的内窥镜检查数据以电子方式从站点传输到用于数据分析的中央数据储存库。质量控制措施确保了数据的完整性和准确性。该执业联盟现在包括68名成人的648名医生和28个州的11个儿科执业地点。在所有成人内窥镜检查结果中，65%来自非学术环境。我们已经成功地完成了预期的研究项目。在目前的方案中，我们将在我们临床实习网络的基础上，进行研究，这将提高胃肠病临床实习的质量。该提案的具体主题是：主题1：实践分析。我们将对内窥镜的使用进行前瞻性分析，测量内窥镜的结果和并发症，实践变异，并确定预测有利或不利结果的可能性的相关性。主题2：将研究转化为实践。我们将开展研究项目，将有关内窥镜检查结果的新信息转化为临床实践。该联盟提供了一个独特的机会来确定新发现对实践的影响。主题3：前瞻性研究。前瞻性研究将集中在缺乏有效性关键证据的临床实践领域。我们已经开发了在实践流程中收集前瞻性数据的方法，跟踪患者随时间的结果，并测量随着时间的推移实践中的变化。主题4：向科学界提供资源。我们已经展示了与广泛的临床研究人员的成功合作，以开发独特适合大型社区实践网络的项目。