Clinical Outcomes Research: An Endoscopic Data Base

临床结果研究：内窥镜数据库

• 批准号: 6867577
• 负责人: DAVID A LIEBERMAN
• 金额: $ 62.96万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6867577
• 关键词: chronic disease /disorder; clinical research; community health services; cooperative study; diagnosis design /evaluation; endoscopy; gastrointestinal disorder; gastrointestinal disorder diagnosis; gastrointestinal imaging /visualization; health care personnel performance; health care quality; health services research tag; human data; human therapy evaluation; information dissemination; information systems; outcomes research; pathologic process; patient /disease registry; patient care management

DESCRIPTION (PROVIDED BY APPLICANT): Pressure to improve the quality and lower the cost of health care has created the need to understand the effectiveness of medical interventions in clinical practice settings. Endoscopy plays an n important role in the diagnosis and management of digestive diseases. Despite widespread use of endoscopy, little is known about outcomes in community-based settings. We developed a practice-based consortium to study endoscopic outcomes. Practice sites utilize a computerized endoscopic report generator to produce endoscopy reports, while simultaneously creating a data file. De-identified endoscopy data is transmitted electronically from sites to a central data repository for data analysis. Quality control measures ensure data integrity and accuracy. The practice consortium now includes 648 physicians in 68 adult, and 11 pediatric practice sites in 28 states. Of all adult endoscopy results, 65 % come from non-academic settings. We have demonstrated successful completion of prospective research projects. In the current proposal, we will build on the foundation of our clinical practice network, to conduct research, which will improve the quality of clinical practice in gastroenterology. The specific themes of this proposal are: Theme 1: Analysis of practice. We will conduct prospective analysis of endoscopic utilization, measure endoscopic findings and complications, practice variation, and identify association, which predict likelihood of favorable or unfavorable outcomes. Theme 2: Translation of research into practice. We will conduct research projects to translate new information about endoscopic outcomes into clinical practice. The consortium provides a unique opportunity to determine hoe new discovery impacts practice. Theme 3: Prospective research. Prospective research will focus on areas of clinical practice that lack critical evidence of effectiveness. We have developed methods for collection of prospective data in the flow of practice, following patient outcomes over time, and measuring changes in practice over time. Theme 4: Provide a resource to the scientific community. We have demonstrated successful collaboration with a wide range of clinical investigators to develop projects that are uniquely suited to a large community-based practice network.

描述（由申请人提供）：