IMAGE GUIDED THERAPY CENTER

我们正在申请资金，以建立一个国家生物医学资源中心， 布里格姆妇女医院（Brigham & Women's Hospital）IGT中心提出， 应用程序将为临床研究者提供一个独特的、集中的基础设施，生物医学！ 工程师和基础科学家在促进和推进IGT的方法和相关的临床 应用.我们将在五个离散的TRD中开发和提供新的创新技术 核心项目：1）计算核心; 2）成像核心; 3）MRI引导治疗 核心; 4）图像引导神经外科核心; 5）聚焦超声治疗 核心这些关键的研究举措代表了技术和临床基础设施的 Resource.他们预计将有显着的效果对未来的几个IGT的方法和临床 并将把联合收割机部队与10支内部部队和7支外部部队合并， 针对IGT的各种基本技术或临床方面的合作。该集合 科学努力包括图像处理和显示工具（3D切片器， 交互式和自适应平台，高性能计算）;动态和自适应MR 成像方法;新型治疗技术（MRI引导聚焦超声）;图像引导 机器人技术;以及从脑肿瘤手术到前列腺干预的几种临床应用。所有 IGT的开发和应用将在现场与我们的合作者进行测试， 直接作为一种服务，以不断增长的IGT社区。我们的首要目标是建立一个中心， 是全国性的，通过培训有效地覆盖广泛的选区， 本资源中正在开发的新技术和方法的使用和传播。

We are requesting funds to establish a national Biomedical Resource Center in Image-guided Therapy (IGT) at the Brigham & Women's Hospital. The IGT Center proposed undejr this application will provide a unique, centralized infrastructure for clinical investigators, biomedica! engineers, and basic scientists in promoting and advancing IGT methods and related clinical applications. We will develop and make available new innovative technologies in five discreteTRD Core Projects: 1) the Computational Core; 2) the Imaging Core; 3) the MRI-guided Therapy Core; 4) the Image-Guided Neurosurgery Core; and 5) the Focused Ultrasound Therapy Core. These key research initiatives represent the technical and clinical infrastructure of the Resource. They are anticipated to have significant effecton several future IGT methods and clinical applications; and will combine forces with 10 internal and 7 external, independently funded Collaborations that address various essential technical or clinical aspects of IGT. Thesecollective scientific efforts include the development of image processing and display tools (3D Slicer, interactive and adaptive platforms, high performance computing); dynamic and adaptive MR imaging methods; novel therapy techniques (MRI-guided focused ultrasound); image-guided robotics; and several clinical applications from brain tumor surgery to prostate interventions. All IGT developments and applications will be tested either on site with our collaborators, ordistributed directly as a service to the growing IGT community. Our overarching goal is to create a Center that is national in character reaching effectively across a broad range of constituencies throughtraining in and dissemination of the novel technologies and methods under development in this Resource.