IMAGE GUIDED THERAPY CENTER

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 描述（由申请人提供）：我们要求继续为布里格姆妇女医院的国家生物医学资源中心提供图像引导治疗（NCIGT）资金。该中心提供了一个独特的，集中的基础设施，在图像引导治疗领域的转化研究。该多学科计划涉及临床研究人员，生物医学工程师和基础科学家，以促进和推进IGT方法和相关的创新临床应用。我们将在六个独立的TRD核心项目中开发和提供新的临床相关技术：1）计算核心; 2）成像核心; 3）图像引导核心; 4）神经外科核心; 5）前列腺核心和6）聚焦超声治疗核心。这些关键的研究举措代表了资源的技术和临床基础设施。预计它们将对未来的几种IGT方法和临床应用产生重大影响。我们将联合收割机力量与7个独立资助的合作（DBP），解决IGT的各种基本技术或临床方面，我们的贡献将产生重大的临床影响。我们的目标是将联合收割机目前成像领域的进展（如分子成像、功能和代谢成像）与先进的治疗（如MRI引导的聚焦超声消融或靶向药物输送、内窥镜手术或机器人）相结合，以实现侵入性更小、更安全、更有效的治疗选择。所有IGT开发和应用程序都将在我们的网站或我们的合作伙伴处进行测试和验证，或直接作为服务分发给不断增长的IGT社区。我们的总体目标是继续成为领先的国家中心，通过服务，培训和传播本资源中正在开发的新技术和方法，有效地覆盖广泛的选区。 公共卫生相关性：这一应用的总体动力是推进和传播新的图像引导治疗技术，有效地加强多学科的研究工作和与先进技术发展相称的基础设施。我们还致力于使我们的技术广泛提供给广大的临床医生社区。我们的使命是开发和实施新颖的创新技术，以减少手术和干预的侵入性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): We are requesting continuation of funds for the National Biomedical Resource Center in Image-guided Therapy (NCIGT) at the Brigham & Women's Hospital. The Center provides a unique, centralized infrastructure for translational research in the area of image-guided therapy. The multidisciplinary program involves clinical investigators, biomedical engineers, and basic scientists in promoting and advancing IGT methods and related innovative clinical applications. We will develop and make available new, clinically relevant technologies in six discrete TRD Core Projects: 1) Computational Core; 2) Imaging Core; 3) Image- Guidance Core; 4) Neurosurgery Core; 5) Prostate Core and 6) Focused Ultrasound Therapy Core. These key research initiatives represent the technical and clinical infrastructure of the Resource. They are anticipated to have significant effect on several future IGT methods and clinical applications. We will combine forces with 7 independently funded Collaborations (DBPs) that address various essential technical or clinical aspects of IGT and our contribution will have significant clinical impact. Our goal is to combine current advances in the field of imaging (like Molecular Imaging, Functional and Metabolic Imaging) with advanced therapies (like MRI-guided Focused Ultrasound ablation or targeted drug delivery, endoscopic surgery or robotics) to achieve less invasive, safer and more effective therapeutic options. All IGT developments and applications will be tested and validated either on our site or at our collaborators, or distributed directly as a service to the growing IGT community. Our overarching goal is to continue being the leading National Center that reaching effectively across a broad range of constituencies through service, training and dissemination of the novel technologies and methods under development in this Resource. PUBLIC HEALTH RELEVANCE: The overarching impetus for this application is to advance and propagate novel image-guided therapy technologies, effectively producing strengthened multidisciplinary research efforts and an infrastructure commensurate with sophisticated technology development. We are also committed to making our technology broadly available to a large community of clinician. Our mission is to develop and implement novel, innovative technologies to decrease the invasiveness of surgeries and interventions.