2008 Cell Biology of the Neuron

2008 神经元细胞生物学

• 批准号: 7492591
• 负责人: JOSHUA M KAPLAN
• 金额: --
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7492591
• 关键词: Affective; Age; Alzheimer' s Disease; Anxiety; Autistic Disorder; Axon; Behavior Disorders; Behavioral; Biological; Biological Models; Brain; Caenorhabditis elegans; Cells; Cellular Neurobiology; Cellular biology; Child health care; Chromosome Pairing; Cognition Disorders; Communication; Complex; Defect; Dendrites; Development; Disease; Drug Addiction; Drug Tolerance; Ensure; Funding; Human; Image; Inherited; Institutes; International; Mental Health; Mission; Molecular; Molecular Genetics; Morphogenesis; National Institute of Child Health and Human Development; National Institute of Drug Abuse; National Institute of General Medical Sciences; National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; Neurons; Neurophysiology - biologic function; Parkinson Disease; Participant; Range; Request for Proposals; Research; Research Personnel; Scientist; Signal Transduction; Supporting Cell; Synapses; Synaptic plasticity; Time; Woman; Work; addiction; base; career; interdisciplinary approach; interest; neurodevelopment; neuromechanism; posters; symposium

DESCRIPTION (provided by applicant): The "Cell Biology of the Neuron" Gordon Conference, to be held for the eighth time in June 2008, has become the premier international meeting for discussing progress in the rapidly moving field of cellular neurobiology. The focus of the meeting will be on the cell biological aspects of neural function. The meeting will encompass a diverse set of interdisciplinary approaches, including genetic, molecular, cellular, biophysical, and behavioral approaches to understanding the brain. A diverse set of model systems will be represented at the meeting, ranging from C. elegans to humans. This year the following themes will be covered: synapse development, pre-synaptic mechanisms, post-synaptic signaling, axon and dendrite morphogenesis, cortical connectivity, imaging circuits, and synaptic plasticity. The chosen speakers are among the most active in the field and are also articulate thinkers who should generate useful discussion by integrating their work and ideas with those in other fields. The format consists of 20 minute talks followed by a discussion of 10 minutes or more. The meeting roster contains a mixture of promising young scientists near the beginning of their careers and established scientists. Nine of the speakers are women and five are from outside the US. In addition, eight slots are being kept open to select speakers for short talks on exciting, late-breaking developments. Most participants (except speakers) will present posters on their work, ensuring maximum communication and exchange of ideas among participants. With its interdisciplinary focus on neural mechanisms, this conference is of special interest for understanding affective and behavioral disorders, hereditary defects in brain development, mental health and drug addiction. The emphasis on neural development and plasticity has relevance for child health and development. The speakers include investigators who are specifically studying the molecular basis of drug tolerance and addiction, affective and cognitive disorders (e.g. anxiety and autism), hereditary defects in brain development, and diseases of aging such as Alzheimer's and Parkinson,s diseases. The conference should be of great potential interest to the missions of institutes including NIMH, NINDS, NICHD, NIA, NIDA and NIAAA. This proposal requests fund to support the "Cell Biology of the Neuron" Gordon Research Conference, to be held in June 2008. This conference brings together a diverse set of neurobiologists, all of whom study the fundamental building blocks of the brain, neurons and synapses. In particular, this meeting will highlight recent discoveries in how the brain develops its complex set of synaptic connections, and how these connections are modified during development, or in different disease states. Thus, this meeting will further the mission of several institutes, including NIGMS, NINDS, NIMH, NIDA, NEI, and NIAAA. .

描述（由申请人提供）：2008年6月第八次举行的“神经元的细胞生物学”会议已成为讨论细胞神经生物学快速运动领域的进展的首要国际会议。会议的重点将放在神经功能的细胞生物学方面。这次会议将涵盖各种跨学科的方法，包括遗传，分子，细胞，生物物理和行为方法来理解大脑。从秀丽隐杆线虫到人类，将在会议上代表各种模型系统。今年将涵盖以下主题：突触发育，突触前机制，突触后信号传导，轴突和树突形态发生，皮质连通性，成像回路和突触可塑性。所选的演讲者是该领域最活跃的人之一，也是表达的思想家，他们应该通过将其工作和思想与其他领域的人们整合在一起来进行有用的讨论。该格式包括20分钟的谈判，然后进行10分钟或更长时间的讨论。会议阵容中包含了有前途的年轻科学家在职业生涯开始和建立科学家的混合物。九个演讲者是女性，五个来自美国以外的人。此外，为精选的演讲者提供了八个插槽，以进行有关令人兴奋的后期发展的简短谈判。大多数参与者（演讲者除外）都会在其工作中介绍海报，以确保参与者之间的最大程度的交流和思想交流。该会议凭借其跨学科的关注，对了解情感和行为障碍，脑发育中的遗传缺陷，心理健康和药物成瘾具有特别的兴趣。对神经发育和可塑性的重视与儿童健康和发育有关。演讲者包括专门研究药物耐受性和成瘾性，情感和认知障碍（例如焦虑和自闭症）的分子基础的研究者，脑发育中的遗传缺陷以及衰老的疾病，例如阿尔茨海默氏症和帕克森氏症。该会议应该引起NIMH，Ninds，Nichd，Nia，NIA，NIDA和NIAAA在内的机构任务的极大兴趣。该提案要求基金支持2008年6月举行的“神经元的细胞生物学”戈登研究会议。该会议汇集了各种各样的神经生物学家，所有这些会议都研究了大脑，神经元和突触的基本建筑块。特别是，这次会议将重点介绍大脑如何发展其复杂的突触连接集以及在发育过程中或不同疾病状态中如何修改这些连接的最新发现。因此，这次会议将进一步促进几个机构的使命，包括Nigms，Ninds，Nimh，Nida，Nei和Niaaa。 。