Communities as Partners in Cancer Clinical Trials

描述（由申请人提供）：2004年AHRQ关于社区参与性研究（CBPR）的循证实践报告得出结论，CBPR方法可以提高研究质量，提高干预质量，加强招聘工作和改善结果。 在2005年的报告中，总统癌症小组看到了CBPR模型的前景，建议对它们进行评估，以确定在癌症临床试验中采用它们的潜力。最近，AHRQ关于“招募代表性不足的人群参加癌症临床试验的知识和信息获取”的证据报告得出结论，“由于许多代表性不足的人群对研究人员和研究机构不信任，应在社区参与性研究的框架内开展研究工作，以提高服务不足的人群对癌症临床试验的参与，在研究的各个阶段都有社区参与。“然而，迄今为止，还没有有组织的国家努力探索在治疗试验设计，招募和保留以及传播中采用CBPR原则的潜力，并为研究，实践和政策制定战略计划。拟议的三部分研究开发会议系列将创造一个机会，使这一点成为现实。社区作为癌症临床试验的合作伙伴：制定研究，实践和政策的战略计划汇集了两个重要但不同领域的研究人员，从业人员，社区领导人和患者倡导者-癌症临床试验和基于社区的参与性研究-探索在治疗试验设计，招募和保留以及传播中采用CBPR原则的潜力，并确定研究的战略计划，实践和政策。建议在2007年10月12日至13日、2007年4月13日至14日和2008年4月11日举行相互借鉴的会议。通过这一系列研究开发的研究重点具有巨大的潜力，可以改变癌症临床研究的进行和资助方式。会议目标包括：确定癌症临床试验目前设计和进行方式的主要局限性。为社区作为癌症临床试验的合作伙伴制定概念框架。回顾社区参与癌症临床试验关键领域的已知情况。探索CBPR原则和方法在癌症临床试验关键领域的应用，确定与社区相关的主要未回答的问题，作为癌症临床试验的合作伙伴，让利益相关者参与制定，传播和实施研究，政策和实践的战略计划。

DESCRIPTION (PROVIDED BY APPLICANT): A 2004 AHRQ evidence-based practice report on community-based participatory research (CBPR) concluded that CBPR approaches can result in improved research quality, enhanced intervention quality, enhanced recruitment efforts and improved outcomes. In its 2005 report, the President's Cancer Panel saw promise in CBPR models, recommending they be evaluated to determine the potential for adopting them in cancer clinical trials. Most recently, the AHRQ evidence report on "Knowledge and Access to Information on Recruitment of Underrepresented Populations to Cancer Clinical Trials" concluded that "Because of many underrepresented populations' mistrust of researchers and of research institutions, research efforts to improve participation of underserved populations in cancer clinical trials should be developed within the framework of community-based participatory research, with community involvement through all phases of the research." However, to date, there have been no organized national efforts to explore the potential of employing CBPR principles in therapeutic trial design, recruitment and retention and dissemination and to define a strategic plan for research, practice and policy. The proposed 3-part research development conference series will create an opportunity to make this happen. Communities as Partners in Cancer Clinical Trials: Developing a Strategic Plan for Research, Practice & Policy brings together researchers, practitioners, community leaders and patient advocates in two important yet disparate fields-cancer clinical trials and community based participatory research-to explore the potential of employing CBPR principles in therapeutic trial design, recruitment and retention and dissemination and to define a strategic plan for research, practice and policy. Conferences that build on each other are proposed to be held October 12-13 2007, April 13-14 2007, and April 11 2008. The research priorities developed through this series have enormous potential to change the way in which cancer clinical research is conducted and funded. Conference objectives include: Identifying the major limitations of the ways cancer clinical trials are currently designed and conducted. Developing a conceptual framework for communities as partners in cancer clinical trials. Reviewing what is known about the involvement of communities in key areas of cancer clinical trials. Exploring the application of CBPR principles and approaches to key areas of cancer clinical trials identifying major unanswered questions pertaining to communities as partners in cancer clinical trials engaging stakeholders in developing, disseminating and implementing a strategic plan for research, policy and practice.