Communities as Partners in Cancer Clinical Trials

描述(由申请人提供)：2004年AHRQ关于社区参与性研究(CBPR)的循证实践报告得出结论，社区参与性研究方法可以导致研究质量提高、干预质量增强、招聘工作增强和结果改善。在2005年的报告中，总统的癌症小组在CBPR模型中看到了希望，建议对它们进行评估，以确定它们在癌症临床试验中采用的潜力。最近，AHRQ的证据报告《关于招募未被充分代表的人群参加癌症临床试验的知识和信息的获取》得出结论说，“由于许多未被充分代表的人群对研究人员和研究机构不信任，应该在社区参与性研究的框架内开展研究，以提高未得到充分服务的人群对癌症临床试验的参与度，并让社区参与到研究的所有阶段。”然而，到目前为止，还没有有组织的国家努力探索在治疗试验设计、招募、保留和传播中采用CBPR原则的潜力，并确定研究、实践和政策的战略计划。拟议的由三部分组成的研究发展会议系列将为实现这一目标创造机会。社区作为癌症临床试验的合作伙伴：制定研究、实践和政策的战略计划将癌症临床试验和基于社区的参与性研究这两个重要但不同领域的研究人员、从业者、社区领袖和患者倡导者聚集在一起，探索在治疗试验设计、招募、保留和传播中采用CBPR原则的潜力，并制定研究、实践和政策的战略计划。相互促进的会议拟于2007年10月12日至13日、2007年4月13日至14日和2008年4月11日举行。通过本系列制定的研究重点具有巨大的潜力，可以改变癌症临床研究的进行和资助方式。会议目标包括：确定目前设计和进行癌症临床试验的方式的主要局限性。为社区开发一个概念框架，作为癌症临床试验的合作伙伴。回顾关于社区参与癌症临床试验关键领域的已知情况。探索将CBPR原则和方法应用于癌症临床试验的关键领域，确定与社区作为癌症临床试验合作伙伴有关的主要悬而未决的问题，让利益相关者参与制定、传播和实施研究、政策和实践的战略计划。

DESCRIPTION (PROVIDED BY APPLICANT): A 2004 AHRQ evidence-based practice report on community-based participatory research (CBPR) concluded that CBPR approaches can result in improved research quality, enhanced intervention quality, enhanced recruitment efforts and improved outcomes. In its 2005 report, the President's Cancer Panel saw promise in CBPR models, recommending they be evaluated to determine the potential for adopting them in cancer clinical trials. Most recently, the AHRQ evidence report on "Knowledge and Access to Information on Recruitment of Underrepresented Populations to Cancer Clinical Trials" concluded that "Because of many underrepresented populations' mistrust of researchers and of research institutions, research efforts to improve participation of underserved populations in cancer clinical trials should be developed within the framework of community-based participatory research, with community involvement through all phases of the research." However, to date, there have been no organized national efforts to explore the potential of employing CBPR principles in therapeutic trial design, recruitment and retention and dissemination and to define a strategic plan for research, practice and policy. The proposed 3-part research development conference series will create an opportunity to make this happen. Communities as Partners in Cancer Clinical Trials: Developing a Strategic Plan for Research, Practice & Policy brings together researchers, practitioners, community leaders and patient advocates in two important yet disparate fields-cancer clinical trials and community based participatory research-to explore the potential of employing CBPR principles in therapeutic trial design, recruitment and retention and dissemination and to define a strategic plan for research, practice and policy. Conferences that build on each other are proposed to be held October 12-13 2007, April 13-14 2007, and April 11 2008. The research priorities developed through this series have enormous potential to change the way in which cancer clinical research is conducted and funded. Conference objectives include: Identifying the major limitations of the ways cancer clinical trials are currently designed and conducted. Developing a conceptual framework for communities as partners in cancer clinical trials. Reviewing what is known about the involvement of communities in key areas of cancer clinical trials. Exploring the application of CBPR principles and approaches to key areas of cancer clinical trials identifying major unanswered questions pertaining to communities as partners in cancer clinical trials engaging stakeholders in developing, disseminating and implementing a strategic plan for research, policy and practice.