权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

CELL IMAGING

细胞成像

基本信息

批准号：
7726481
负责人：
FRED BUNZ
金额：
$ 7.44万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/7726481
关键词：
Animals Area Argon Arts Brightfield Microscopy Caliber Cancer Biology Cancer Center Carbon Dioxide Cell Cycle Cell Proliferation Cells Chemicals Chromosomes Color Complex Computer software Computers Condition Confocal Microscopy Consultations Core Facility Cultured Cells Cytogenetics Cytometry Data Dextromethorphan Dissection Engineering Environment Equipment Evaluation Experimental Designs Floor Fluorescence Gene Expression Genomics Hand Hematologic Neoplasms Housing Human Resources Image Image Analysis Imagery Imaging technology Immunophenotyping Incubators Ions Label Lasers Life Light Malignant Neoplasms Membrane Potentials Microdissection Microscope Microscopic Microscopy Mission Molecular Analysis Mus Nature Neoplasm Metastasis Photography Photometry Pliability Population Principal Investigator Proteomics Range Research Research Personnel Resolution Sampling Scientist Services Signal Transduction Spottings System Techniques Temperature Therapeutic Therapeutic Agents Time Tissues Training Transfection Tube Urologic Oncology Viral Cancer Visual anticancer research cellular imaging charge coupled device camera computer program data acquisition design digital foot innovation instrument instrumentation malignant breast neoplasm member neoplastic cell oncology programs release of sequestered calcium ion into cytoplasm research study response satisfaction stereoscopic success tumor tumor growth user-friendly

项目摘要

Since the inception of the Cell Imaging Core Facility in September of 1999, its mission has been to provide state-of-the-art cell imaging technologies to Cancer Center members. This includes different forms of light and fluroescence microscopes, stereo and confocal microscopy, and a laser microdissection system. Images can be captured with several video and CCD cameras, analyzed and manipulated with several image analysis software programs. In addition, the Core provides analytical cytometry services like immunophenotyping and cell cycle analysis. All scientists have the opportunity for expert consultation prior to and during their experiments and receive continuous technical support by the Core personnel throughout the use of any core equipment. Core technicians evaluate the facility's equipment routinely and engage in frequent technical training in order to maintain and warrant the constantly evolving needs and opportunities in this technical research area. In 2004, 57 different groups led by principal investigators from all programs of the Center, including cancer biology, hematologic malignancies, chemical therapeutics, cancer immunlogy, urologic oncology, Gl cancer, breast cancer, and viral oncology, benefited from these core services.

自1999年9月细胞成像核心设施成立以来，其任务一直是为癌症中心成员提供最先进的细胞成像技术。这包括不同形式的光学显微镜和荧光显微镜、立体显微镜和共聚焦显微镜，以及激光显微解剖系统。可以用几个视频和CCD摄像机捕获图像，并用几个图像进行分析和处理分析软件程序。此外，核心还提供分析细胞分析服务，如免疫表型和细胞周期分析。所有科学家都有机会在研究之前进行专家咨询并在整个实验期间获得核心人员的持续技术支持使用任何核心设备。核心技术人员定期对设施设备进行评估，并频繁参与技术培训，以保持和保证不断变化的需求和机会技术研究领域。2004年，由联合国儿童基金会所有项目的首席调查人员领导的57个不同的小组中心，包括癌症生物学，血液恶性肿瘤，化学疗法，癌症免疫学，泌尿外科肿瘤学、G1癌症、乳腺癌和病毒肿瘤学受益于这些核心服务。