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Identification and characterization of novel proteins in endosomal cholesterol transport

Identification and characterization of novel proteins in endosomal cholesterol transport
内体胆固醇转运中新型蛋白质的鉴定和表征
批准号:
nhmrc : 1041301
负责人:
Prof Andrew Brown
金额:
$36.05万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31

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中文摘要
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英文摘要
Abnormal subcellular distribution of cholesterol is associated with a number of common diseases including heart disease and Alzheimer’s disease. The overall aim of this proposal is to identify and characterize novel molecules that regulate the transport of intracellular cholesterol. Results from the proposed studies will provide important insights into the molecular mechanisms governing intracellular cholesterol transport and distribution, and will lead to better treatment strategies against heart disease and dementia.
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Lipid trafficking at membrane contact sites: the role of Oxysterol-Binding Protein-Related Protein 5 and 8 (ORP5 and ORP8)
  • 批准号:
    nhmrc : 1141939
  • 项目类别:
    Project Grants
  • 资助金额:
    $31.53万
  • 财政年份:
    2018
  • 负责人:
    Prof Andrew Brown
  • 依托单位:
The role of adipose tissue cholesterol in metabolic diseases
  • 批准号:
    nhmrc : 1141938
  • 项目类别:
    Project Grants
  • 资助金额:
    $60.06万
  • 财政年份:
    2018
  • 负责人:
    Prof Andrew Brown
  • 依托单位:
Lipid trafficking at membrane contact sites: the role of Oxysterol-Binding Protein-Related Protein 5 and 8 (ORP5 and ORP8)
  • 批准号:
    nhmrc : GNT1141939
  • 项目类别:
    Project Grants
  • 资助金额:
    $46.64万
  • 财政年份:
    2018
  • 负责人:
    Prof Andrew Brown
  • 依托单位:
The role of adipose tissue cholesterol in metabolic diseases
  • 批准号:
    nhmrc : GNT1141938
  • 项目类别:
    Project Grants
  • 资助金额:
    $88.83万
  • 财政年份:
    2018
  • 负责人:
    Prof Andrew Brown
  • 依托单位:
海外基金