Niemann Pick disease type C and intracellular sterol trafficking
Niemann Pick disease type C and intracellular sterol trafficking
批准号:
nhmrc : 510271
负责人:
Prof Andrew Brown
金额:
$21.19万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2010-12-31
中文摘要
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英文摘要
Abnormal distribution of cellular cholesterol causes Nieman Pick Disease type C (NP-C), and is also strongly associated with common neurodegenerative diseases such as Alzheimer's disease. We aim to understand the molecular mechanisms by which cholesterol is sorted and transported in the cell. Our results may help develop effective therapeutic strategies against NP-C, Alzheimers' disease and other cholesterol related disorders.
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Lipid trafficking at membrane contact sites: the role of Oxysterol-Binding Protein-Related Protein 5 and 8 (ORP5 and ORP8)
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依托单位:
Lipid trafficking at membrane contact sites: the role of Oxysterol-Binding Protein-Related Protein 5 and 8 (ORP5 and ORP8)
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项目类别:Project Grants
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财政年份:2018
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负责人:Prof Andrew Brown
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依托单位:
The role of adipose tissue cholesterol in metabolic diseases
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批准号:nhmrc : GNT1141938
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资助金额:$88.83万
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Navigating flux control through a branched metabolic pathway
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批准号:DP170101178
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项目类别:Discovery Projects
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资助金额:$27.61万
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财政年份:2017
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Characterising an important control point in cholesterol synthesis beyond HMG-CoA reductase
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财政年份:2014
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Identification and characterization of novel proteins in endosomal cholesterol transport
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财政年份:2013
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Controlling interactive music performance: enhancing live performances by human musicians and algorithmic computer systems
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Novel control points in cholesterol synthesis
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批准号:nhmrc : 1008081
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项目类别:Project Grants
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资助金额:$24.45万
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财政年份:2011
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Smart Music: Combining music perception and algorithmic composition
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财政年份:2009
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The role of seipin in lipid metabolism and adipogenesis
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项目类别:NHMRC Project Grants
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资助金额:$26.52万
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财政年份:2009
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Role of an Endogenously Synthesised Sterol in Regulating Cholesterol Removal from the Macrophage
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Defining the Regulatory Pool of Cholesterol in the Mammalian Cell
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批准号:DP0558041
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依托单位:
Developing techniques for evolutionary music
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批准号:DP0452588
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项目类别:Discovery Projects
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资助金额:$7.72万
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财政年份:2004
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负责人:Prof Andrew Brown
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依托单位:
国内基金
海外基金
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