DIAGNOSTIC PARASITOLOGY CORE

诊断寄生虫学核心

• 批准号: 7562323
• 负责人: FRANK B. COGSWELL
• 金额: $ 3.04万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7562323
• 关键词: Animals; Anticoagulants; Balantidium; Blood; Blood specimen; Breeding; Calendar; Clinical; Clinical Investigator; Computer Retrieval of Information on Scientific Projects Database; Consultations; Diagnostic; Diagnostic Services; Enterobius; Feces; Funding; Giardia lamblia; Grant; Institution; Intestines; Laboratories; Laboratory Animals; Mites; Monkeys; Mus; Parasites; Parasitology; Process; Quarantine; Reporting; Research; Research Personnel; Research Project Grants; Resources; Rodent; Sampling; Services; Source; Strongyloides; Surveys; Techniques; Thick; Trichocephalus trichiura; United States National Institutes of Health; Veterinarians; animal colony; enzootic; nonhuman primate; pathogen

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. All animals entering quarantine from outside sources are examined for the presence of blood and intestinal parasites before they enter the colony. Additionally, the Parasitology Service Laboratory provides diagnostic support to investigators and clinical veterinarians whenever monkeys are suspected of harboring parasites. Mice in the rodent colony are also periodically checked for mites and pinworms prospectively. The laboratory also collaborates with researchers outside the Center when projects involving non-human primates require diagnostic services. During the calendar year 2006, the laboratory processed 2,398 clinical samples, including 444 stool samples from animals in quarantine, and 477 stool samples from animals assigned to research projects. The lab also examined 466 blood samples by the Knott's technique and thick and thin blood smears from colony animals. Pathogenic parasites reported included Giardia lamblia (1.5%), Balantidium coli (17%), Strongyloides fulleborni (32%), and Trichuris trichiura (28%). The laboratory, recognized as one of the few facilities in the world devoted to parasites of non-human primates, provided pictures of parasi6es for recent revisions in Flynn's Parasites of Laboratory Animals. The laboratory also examined a mite sample from the Tulane vivarium and will continue to aid this facility whenever they request consultation. In addition to the above samples, the laboratory is also examining blood and fecal samples in direct support of a survey of enzootic pathogens from the breeding colony.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 所有从外部进入检疫的动物在进入殖民地之前都要检查血液和肠道寄生虫的存在。此外，每当猴子被怀疑藏有寄生虫时，寄生虫学服务实验室就会为调查人员和临床兽医提供诊断支持。啮齿动物群体中的老鼠也会定期接受检查，看是否有螨虫和蛔虫。当涉及非人类灵长类动物的项目需要诊断服务时，该实验室还与中心外的研究人员合作。 在2006历年期间，该实验室处理了2398份临床样本，其中包括444份来自隔离动物的粪便样本，以及477份来自分配给研究项目的动物的粪便样本。该实验室还用克诺特技术检测了466个血液样本，并对群体动物进行了粗细血液涂片。报告的致病寄生虫包括蓝氏贾第鞭毛虫(1.5%)、结肠巴兰蒂氏菌(17%)、富勒伯氏类圆线虫(32%)和鞭毛虫(28%)。该实验室被认为是世界上为数不多的专门研究非人类灵长类寄生虫的设施之一，它为弗林的《实验动物寄生虫》最近的修订版提供了寄生虫的照片。该实验室还检查了杜兰间隔菌的一份尘螨样本，并将在他们提出咨询请求时继续协助该设施。 除了上述样本外，实验室还在检查血液和粪便样本，以直接支持对繁殖群体的地方性病原体的调查。