DIAGNOSTIC PARASITOLOGY CORE

诊断寄生虫学核心

• 批准号: 7716252
• 负责人: FRANK B. COGSWELL
• 金额: $ 2.4万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-21 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7716252
• 关键词: Animals; Anticoagulants; Bacteriology; Balantidium; Blood; Blood specimen; Breeding; Calendar; Clinical; Computer Retrieval of Information on Scientific Projects Database; Diagnostic; Diagnostic Services; Enterobius; Feces; Funding; Giardia lamblia; Grant; Institution; Intestines; Laboratories; Methods; Mites; Monkeys; Mus; Parasites; Parasitic Diseases; Parasitology; Process; Quarantine; Reporting; Research; Research Personnel; Research Project Grants; Resources; Rodent; Sampling; Services; Source; Strongyloides; Surveys; Techniques; Thick; Trichocephalus trichiura; United States National Institutes of Health; Veterinarians; Veterinary Medicine; animal colony; egg; enzootic; nonhuman primate; pathogen

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Parasitology Service Laboratory provides diagnostic support to clinical veterinarians as well as investigators, whenever monkeys are suspected of harboring parasites and helps provide the first line of defense against parasitic disease in the colony. All animals entering quarantine from outside sources are examined for the presence of blood and intestinal parasites before they enter the colony. Additionally, mice in the rodent colony are also periodically checked for mites and pinworms prospectively. The laboratory also collaborates with researchers outside the Center when projects involving non-human primates require diagnostic services. During the calendar year 2007, the laboratory processed 2,321 stool samples, including 520 stool samples from animals in quarantine, and 248 stool samples from animals assigned to research projects. The lab also examined 44 blood samples by the Knott's technique and 265 thick and thin blood smears from colony animals. Pathogenic parasites reported included Strongyloides fulleborni (26%),Trichuris trichiura (39%) Giardia lamblia (6%), and Balantidium coli (10%). The laboratory also acted in support of a project by Dr. Erin Ribka (Division of Veterinary Medicine) by performing egg quantitation using the Kato-Katz method on 170 separate stool samples. In addition to the above samples, the laboratory is also examining blood and fecal samples in direct support of a survey of enzootic pathogens from the breeding colony, a project of Dr. Frank Cogswell (Division of Bacteriology & Parasitology).

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 寄生虫学服务实验室为临床兽医和研究人员提供诊断支持，每当猴子被怀疑携带寄生虫时，并帮助提供殖民地寄生虫病的第一道防线。所有从外部进入隔离区的动物在进入殖民地之前，都要检查是否存在血液和肠道寄生虫。此外，还定期前瞻性检查啮齿动物群中的小鼠是否有螨和蛲虫。当涉及非人类灵长类动物的项目需要诊断服务时，该实验室还与中心外的研究人员合作。在2007日历年，实验室处理了2 321份粪便样本，包括520份来自检疫动物的粪便样本和248份来自分配给研究项目的动物的粪便样本。该实验室还通过Knott技术检查了44份血液样本和265份来自殖民地动物的厚和薄血液涂片。报告的病原性寄生虫包括类圆线虫（26%）、鞭虫（39%）、贾第鞭毛虫（6%）和结肠小袋纤毛虫（10%）。该实验室还支持Erin Ribka博士（兽医部门）的一个项目，使用Kato-Katz方法对170份单独的粪便样本进行鸡蛋定量。除了上述样本外，实验室还检查了血液和粪便样本，以直接支持对繁殖地的地方病病原体的调查，这是Frank Cogswell博士（细菌学和寄生虫学部门）的一个项目。