ESSENTIAL AND NON-ESSENTIAL ELEMENT BIOAVAILABILITY FROM SUBSISTENCE FOODS

生计食品中的必需元素和非必需元素的生物利用度

• 批准号: 7719956
• 负责人: Todd M. O'Hara
• 金额: $ 19.32万
• 依托单位: UNIVERSITY OF ALASKA FAIRBANKS
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719956
• 关键词: Alaska; Applications Grants; Arctic Regions; Award; Biological Availability; Biomedical Research; Centers of Research Excellence; Communicable Diseases; Computer Retrieval of Information on Scientific Projects Database; Diagnostic; Disease; Ecology; Elements; Exposure to; Fishes; Food; Funding; Gasterosteidae; Glacier; Grant; Health; Human; IACUC; Institution; Laboratories; Mentors; Modeling; Nutrient; Oregon; Pathway interactions; Perchlorates; Phoca vitulina; Population; Preparation; Problem Solving; Protocols documentation; Reindeer; Research; Research Personnel; Resources; Salmon; Sampling; Science; Services; Source; Students; Toxicology; U-Series Cooperative Agreements; United States National Institutes of Health; Universities; Update; member; nutrition; response; seal; terrestrial marine interface

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Biomedical Research Focus in 25 words or less. Wildlife Toxicology Laboratory is contaminants, health & nutrition of subsistence use & wildlife. We are not solely "research" we are involved with diagnostics/problem solving. 1. Update on science, proposals/grants, projects. Proposals/Grants: CANHR (COBRE) renewal funded ($1.2KK over 5 years for our assessment of nutrients and contaminants in salmon, reindeer, and bearded seals in Mekoryuk). IACUC protocol 06-20 Approval 06/07/2007 IACUC protocol 07-09 Approval 01/16/2008 IACUC protocol 07-30 Approval 06/12/2007 IACUC protocol 07-37 Approval 08/14/2007 IACUC protocol 07-49 Approval 12/18/2007 IACUC protocol 08-02 Approval 01/17/2008 NSF major proposal ($2+ million, O'Hara PI) submitted January 2007 in response to the rfp "Ecology of Infectious Diseases" entitled "Modeling apex predator disease agents at the arctic Alaska marine-terrestrial interface". NOT FUNDED. NIH R01: Two major efforts underway Two species fish model for perchlorate submitted combining efforts of UAA (PI Von Hippel), University of Oregon and UAF to determine underlying mechanism for masculinization of stickleback fish from exposure to perchlorate. Please discuss details with Frank at UAA. Hg in Fish of Alaska: R01 in preparation under guidance of mentors Gary Myers and Dave Eaton, and EAC member Jim Berner (JB likely Co-Inv). Likely to involve direct human sampling and assessment! Non-NIH, Non-NSF (those less prestigious awards) Harbor seals: Hoonah Indian Association (USFWS funds) and National Park Service Cooperative agreement combine for about $250K: because of 75% decline in population of harbor seals in Glacier Bay (Alaska) we have been asked to assist with health, disease and contaminants assessment  pathways to humans. Ms. Darce Holcomb is the MS student on this.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 生物医学研究重点在 25 个字以内。 野生动物毒理学实验室致力于维持生计用途和野生动物的污染物、健康和营养。我们不仅仅是“研究”，我们还参与诊断/解决问题。 1. 科学、提案/赠款、项目的最新信息。 提案/赠款： CANHR (COBRE) 续订资助（5 年内 1.2 KK 美元，用于评估 Mekoryuk 的鲑鱼、驯鹿和髯海豹的营养和污染物）。 IACUC 协议 06-20 批准 06/07/2007 IACUC 协议 07-09 批准 01/16/2008 IACUC 协议 07-30 批准 06/12/2007 IACUC 协议 07-37 批准 08/14/2007 IACUC 协议 07-49 批准 12/18/2007 IACUC 协议 08-02 批准 01/17/2008 NSF 主要提案（200 万美元以上，O'Hara PI）于 2007 年 1 月提交，以响应标题为“在北极阿拉斯加海洋-陆地界面模拟顶级捕食者疾病病原体”的 RFP“传染病生态学”。没有资金。 NIH R01：两项重大工作正在进行中 UAA (PI Von Hippel)、俄勒冈大学和 UAF 联合提交了两种高氯酸盐鱼类模型，以确定刺鱼因接触高氯酸盐而雄性化的潜在机制。请与 UAA 的 Frank 讨论细节。 阿拉斯加鱼中的汞：R01 在导师 Gary Myers 和 Dave Eaton 以及 EAC 成员 Jim Berner（JB 可能是 Co-Inv）的指导下准备中。可能涉及直接人体采样和评估！ 非 NIH、非 NSF（那些不太有声望的奖项） 斑海豹：胡纳印第安协会（USFWS 资金）和国家公园管理局合作协议合计金额约为 25 万美元：由于冰川湾（阿拉斯加）的斑海豹数量下降了 75%，我们被要求协助人类进行健康、疾病和污染物评估。 Darce Holcomb 女士是这方面的硕士生。